Serum homocysteine in pre-eclampsia and eclampsia.

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dc.contributor.authorHoque, Md Mozammelen_US
dc.contributor.authorBulbul, Taniaen_US
dc.contributor.authorMahal, Monzarinen_US
dc.contributor.authorIslam, Nur-A-Farzanaen_US
dc.contributor.authorFerdausi, Muniraen_US
dc.date.accessioned2008-04-12en_US
dc.date.accessioned2009-05-27T03:47:23Z
dc.date.available2008-04-12en_US
dc.date.available2009-05-27T03:47:23Z
dc.date.issued2008-04-12en_US
dc.descriptionBangladesh Medical Research Council Bulletin.en_US
dc.description.abstractPre-eclampsia and eclampsia are common obstetrical problem causing adverse effects on pregnancy outcome. Large bodies of evidences suggest that hyperhomocysteinemia is a causal factor of pre-eclampsia/eclampsia. This study designed to explore the association between hyperhomocysteinemia and pre-eclampsia/eclampsia, the knowledge of which expected to be used for prevention of pre-eclampsia and eclampsia. In a case-control study serum homocysteine was measured in 136 controls (healthy pregnant), 84 pre-eclamptic and 120 eclamptic pregnant women. Serum homocysteine in patients with pre-eclampsia (9.54 +/- 3.21 micromol/L) and eclampsia (10.57 +/- 3.39 micromol/L) found to be significantly increased compared to controls (6.86 +/- 2.47 micromol/L) (p < 0.001). Between pre-eclampsia and eclampsia, homocysteine found to be raised more in eclampsia compared to pre-eclampsia (p < 0.03). In conclusion, hyperhomocysteinemia is associated with pre-eclampsia as well as eclampsia, but in eclampsia the severity of homocysteine elevation is more compared to that in pre-eclampsia.en_US
dc.description.affiliationDepartment of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. m_mhoque@yahoo.comen_US
dc.identifier.citationHoque MM, Bulbul T, Mahal M, Islam NA, Ferdausi M. Serum homocysteine in pre-eclampsia and eclampsia. Bangladesh Medical Research Council Bulletin. 2008 Apr; 34(1): 16-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/472
dc.language.isoengen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/indexen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/article/view/1165/1178en_US
dc.subject.meshAdulten_US
dc.subject.meshBangladeshen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshEclampsia --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHomocysteine --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshHyperhomocysteinemia --blooden_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshPre-Eclampsia --blooden_US
dc.subject.meshPregnancyen_US
dc.subject.meshRisk Factorsen_US
dc.titleSerum homocysteine in pre-eclampsia and eclampsia.en_US
dc.typeJournal Articleen_US
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