Diagnosis of neurocysticercosis by enzyme-linked immunosorbent assay.

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dc.contributor.authorDas, Aen_US
dc.contributor.authorGoyal, Renuen_US
dc.contributor.authorSaxena, Sonalen_US
dc.contributor.authorSingh, N Pen_US
dc.date.accessioned2005-10-28en_US
dc.date.accessioned2009-05-31T17:50:48Z
dc.date.available2005-10-28en_US
dc.date.available2009-05-31T17:50:48Z
dc.date.issued2005-10-28en_US
dc.description.abstractNeurocysticercosis, a disease caused by larvae of T solium produces variable and non-specific symptoms. Computerised tomography, magnetic resonance imaging, immunological tests in the serum and cerebrospinal fluid are available options to diagnose the condition. Two hundred serum samples collected and stored frozen at -20 degrees C and were tested for cysticercosis by commercial Melotest cysticercosis kit. Diagnosis was confirmed by other investigations. After the confirmative diagnosis results of ELISA for cysticercosis were compared and the values of sensitivity, specificity, prevalence and precision were obtained along with positive and negative predictive values. Overall prevalence was found to be 10% in this study. Only 26.5% serologically positive cases had neurocysticercosis positively. The positive predictive value of the serological test was only 26.4% suggesting that the diagnosis of neurocysticercosis by ELISA is not reliable in an endemic area.en_US
dc.description.affiliationDepartment of Microbiology, University College of Medical Sciences, GTB Hospital, Delhi 110095.en_US
dc.identifier.citationDas A, Goyal R, Saxena S, Singh NP. Diagnosis of neurocysticercosis by enzyme-linked immunosorbent assay. Journal of the Indian Medical Association. 2005 Oct; 103(10): 528-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/105427
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshHumansen_US
dc.subject.meshNeurocysticercosis --blooden_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshTaenia solium --isolation & purificationen_US
dc.titleDiagnosis of neurocysticercosis by enzyme-linked immunosorbent assay.en_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
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