Clinicoetiological profile and outcome of acute febrile illness with thrombocytopenia in children: a hospital based prospective study

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dc.contributor.authorAgarwal, Priyankaen_US
dc.contributor.authorDas, Ratan Kumaren_US
dc.contributor.authorDash, Dillip Kumaren_US
dc.contributor.authorKumari, Mamtaen_US
dc.contributor.authorMohanty, M. D.en_US
dc.date.accessioned2020-09-24T07:48:21Z
dc.date.available2020-09-24T07:48:21Z
dc.date.issued2020-06
dc.description.abstract'Background: Thrombocytopenia is often the most commonly encountered clinical condition in this routine practice. Etiological causes being numerous, often pose a challenge in evaluating and treating the patients. The objective of this study was to find out the different causes and clinical profile of fever with thrombocytopenia in children aged 1month to 14 year who were admitted in this set up.Methods: This was a prospective study done on 200 patients with thrombocytopenia admitted IMS AND SUM Hospital, BBSR with various complaints, during the period of 01 August 2017 to 01 August 2019. This study includes age group 1months to 14 years.Results: The highest incidence of thrombocytopenia belonged to the age group 11-14 years (22.5%) followed by 6-9 years (19.5%) and 3-6 years (18%). Incidence of thrombocytopenia was more in male child (58.5%) as compared to female child (41.5%). the most common cause of thrombocytopenia was dengue (50%), Scrub typhus (34%) septicaemia (17.5%) followed by malaria (10.5%). Among the infectious aetiology severe thrombocytopenia was seen more in dengue (25%) and scrub typhus (34.5%) but evidence of bleeding was seen more in sepsis (34.2%) even with higher platelet count which may be explained by associated multi organ failure.Conclusions: Infections like malaria, dengue, leptospirosis and septicaemia were the common causes of thrombocytopenia along with scrub typhus. Whenever thrombocytopenia is detected further investigations can help us in reaching a correct diagnosis in the majority of the cases so that appropriate treatment can be given and also to avoid unnecessary platelet transfusion to prevent transfusion related complications.en_US
dc.identifier.affiliationsDepartment of Pediatrics, IMS and SUM Hospital, Bhubaneswar, Odisha, Indiaen_US
dc.identifier.citationAgarwal Priyanka, Das Ratan Kumar, Dash Dillip Kumar, Kumari Mamta, Mohanty M. D.. Clinicoetiological profile and outcome of acute febrile illness with thrombocytopenia in children: a hospital based prospective study. International Journal of Contemporary Pediatrics. 2020 Jun; 7(6): 1284-1291en_US
dc.identifier.issn2349-3283
dc.identifier.issn2349-3291
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/204624
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3291.ijcp20202135en_US
dc.subjectBleeding Manifestationsen_US
dc.subjectDengue Feveren_US
dc.subjectMalariaen_US
dc.subjectSepticemiaen_US
dc.subjectThrombocytopeniaen_US
dc.titleClinicoetiological profile and outcome of acute febrile illness with thrombocytopenia in children: a hospital based prospective studyen_US
dc.typeJournal Articleen_US
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