Tuberculosis and Leprosy: A Rare Case of Dual Mycobacterial Infection

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dc.contributor.authorGuliani, Aen_US
dc.contributor.authorThukral, G.en_US
dc.date.accessioned2025-05-09T11:00:45Z
dc.date.available2025-05-09T11:00:45Z
dc.date.issued2024-12
dc.description.abstractLeprosy and tuberculosis (TB) share geographic endemicity. The degree of cross-immunity of one against the other makes coinfection an uncommon clinical encounter. Here, we report a 35-year-old male patient who presented with a history of fever and cough for a month. He had ulnar claw deformity and multiple hypopigmented lesions since childhood. Chest radiograph showed left middle zone airway opacification and HR-CT revealed left lingular consolidation. Cartridge-based Nucleic Acid Amplification Test (CBNAAT) confirmed Mycobacterium tuberculosis and ulnar nerve biopsy confirmed borderline leprosy. The patient had no predisposing factors for TB other than the underlying leprosy. The dual infection was approached with WHO-recommended antitubercular treatment along with dapsone, clofazimine, and prednisolone for leprosy. Prednisolone was gradually tapered and discontinued, while the other medications were maintained. The patient’s overall health showed improvement on follow-up. The possibility of concomitant leprosy and TB must be considered by the clinicians to obtain an accurate clinical diagnosis, advise a comprehensive management plan, and avoid treatment-related complications.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, Ohio, United States of Americaen_US
dc.identifier.affiliationsDepartment of Medicine, Kasturba Medical College, Mangaluru, Karnataka, Indiaen_US
dc.identifier.citationGuliani A, Thukral G.. Tuberculosis and Leprosy: A Rare Case of Dual Mycobacterial Infection . The Indian Journal of Chest Diseases and Allied Sciences. 2024 Dec; 66(4): 143-145en_US
dc.identifier.issn0377-9343
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/245836
dc.languageenen_US
dc.publisherJaypee Brothers Medical Publishers Pvt. Ltd.en_US
dc.relation.issuenumber4en_US
dc.relation.volume66en_US
dc.source.urihttps://doi.org/10.5005/jp-journals-11007-0131en_US
dc.subjectCase reporten_US
dc.subjectCoinfectionen_US
dc.subjectLeprosyen_US
dc.subjectTuberculosisen_US
dc.titleTuberculosis and Leprosy: A Rare Case of Dual Mycobacterial Infectionen_US
dc.typeJournal Articleen_US
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