Acute abdomen in patients receiving chemotherapy.

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dc.contributor.authorPandey, Men_US
dc.contributor.authorMathew, Aen_US
dc.contributor.authorGeetha, Nen_US
dc.contributor.authorSebastian, Pen_US
dc.contributor.authorAhamed, I Men_US
dc.contributor.authorNair, M Ken_US
dc.date.accessioned2009-05-28T06:30:43Z
dc.date.available2009-05-28T06:30:43Z
dc.date.issued2001-06-21en_US
dc.description.abstractOBJECTIVE: To assess the incidence of acute abdomen in patients receiving chemotherapy and to evaluate the factors affecting the clinical decision-making. MATERIAL AND METHODS: Retrospective analysis of surgical oncology references for the patients developing acute abdomen while receiving chemotherapy was carried out. A surgical oncologist reviewed each referral and a full work-up was carried out. Surgical interventions were carried out as and when deemed necessary. Response to treatment, whether surgical or conservative, was used as main outcome variable. RESULTS: Mean age of the patients was 37 years (7-58 years). Half of the patients were receiving chemotherapy for lymphoproliferative disorders, 13 for haematological malignancies and 3 for ovarian cancer. Clinical diagnosis was of acute appendicitis in 13, paralytic ileus in 9, typhilitis in 3 and intestinal perforation in 2, acute intestinal obstruction in 3, and obstructed hernia and intussception in one each. Six patients underwent surgery. Two patients expired postoperatively of progressive septicaemia and multi-system organ failure. CONCLUSION: Evaluation of cancer patients on chemotherapy is difficult. Tenderness, presence of peritoneal signs and absence of exaggerated bowel sounds are most important clinical signs, however they may be blunted by progressive neutropenia or corticosteroid administration. Decision to operate, should be made with extreme caution as mortality and morbidity after surgery is high.en_US
dc.description.affiliationDepartment of Surgical Oncology, Regional Cancer Centre, Medical College P.O., Trivandrum-695011, Kerala, India.en_US
dc.identifier.citationPandey M, Mathew A, Geetha N, Sebastian P, Ahamed IM, Nair MK. Acute abdomen in patients receiving chemotherapy. Indian Journal of Cancer. 2001 Jun-Dec; 38(2-4): 68-71en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/49952
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAbdomen, Acute --chemically induceden_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAntineoplastic Agents --adverse effectsen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHematologic Neoplasms --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshLymphoproliferative Disorders --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.titleAcute abdomen in patients receiving chemotherapy.en_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
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