Flunarizine: a review of its role in migraine prophylaxis
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Date
2020-02
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Flunarizine, a potent calcium channel blocker has been used for more than three decades for the prophylactic management of migraine. Theories suggest that flunarizine may act through multiple mechanisms such as inhibition of cortical spreading depression, neurogenic inflammation and channelopathy. Flunarizine is efficacious in the management of various types of migraines such as common, classical, vestibular, abdominal, hemiplegic and pediatric migraine. It has a manageable safety profile with weight gain and drowsiness being commonly reported.
Description
Keywords
Calcium channel, Channelopathy, Flunarizine, Hemiplegic, Migraine, Prophylaxis
Citation
Francis M. V., Singh Sumit, Goyal Vishal, Keny Mukundraj. Flunarizine: a review of its role in migraine prophylaxis. International Journal of Research in Medical Sciences. 2020 Feb; 8(2): 786-793