Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses

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dc.contributor.authorSingh, Rekhaen_US
dc.contributor.authorMittal, Vanien_US
dc.contributor.authorBali, Irbinder Kouren_US
dc.contributor.authorArora, Sunilen_US
dc.contributor.authorKumar, Rajen_US
dc.date.accessioned2020-11-18T10:02:13Z
dc.date.available2020-11-18T10:02:13Z
dc.date.issued2020-07
dc.description.abstractBackground: Fine Needle Aspiration Cytology (FNAC) has proven to be less costly and less invasive procedure than biopsy for diagnosing benign and malignant lesions. Of the two methods liquid based cytology (LBC) and conventional cytology (CC), LBC has been standardized as more efficacious in reporting in Gynaecological cases. But, this is still lacking in non-gynaecological cases and many studies are now focusing on studying LBC due to its proven advantages in Pap smear evaluation.Methods: An observational study of 72 patients with lung mass and 11 with mediastinal mass was done for a period of six months in a tertiary care hospital in Gurugram to compare the diagnostic efficacy of LBC and CC in fine needle aspirates from lung/mediastinal mass.Results: Of the 83 cases, reporting of LBC was adequate in 75 cases and CC in only 53 cases. LBC was better when differentiating malignant and benign lesions than CC. CC smears had better cellularity in comparison to LBC smears (36%), but rest cytological features of cytoplasmic detailing, cell architecture, less background debris and blood were all more appreciable in LBC smears than CC preparations.Conclusions: LBC is a better method than conventional smear for smear preparation and processing of aspirates obtained from lung and mediastinal mass.en_US
dc.identifier.affiliationsDepartment of Pathology, Strand Life Sciences, Gurugram, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, FMHS and SGT Hospital, Gurugram, Haryana, Indiaen_US
dc.identifier.citationSingh Rekha, Mittal Vani, Bali Irbinder Kour, Arora Sunil, Kumar Raj. Diagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal masses. International Journal of Research in Medical Sciences. 2020 Jul; 8(7): 2413-2420en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212502
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20202543en_US
dc.subjectConventional cytologyen_US
dc.subjectFNACen_US
dc.subjectLiquid based cytologyen_US
dc.subjectLung massen_US
dc.subjectMediastinal massen_US
dc.titleDiagnostic efficacy of FNAC by liquid based technique versus conventional smear in lung and mediastinal massesen_US
dc.typeJournal Articleen_US
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