Comparative Evaluation of Midazolam and Ketamine with Midazolam Alone as Oral Premedication in Children

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dc.contributor.authorModi, Shreyaen_US
dc.contributor.authorPatel, Subhashen_US
dc.date.accessioned2023-06-17T08:58:43Z
dc.date.available2023-06-17T08:58:43Z
dc.date.issued2022-01
dc.description.abstractIntroduction: The main aims of preanesthetic medication in children are to reduce anxiety associated with the unfamiliar environment, facilitate the separation of the child from their parent and allow smooth induction of anesthesia. Both oral midazolam and oral ketamine fulfil many of these characteristics and are useful. Method: As 48 patients of ASA grade 1 and 2, aged between 2-10 years undergoing elective surgery were allocated to one of two study groups using random numbers: Group 1 received midazolam 0.5mg/kg and group 2 received midazolam 0.25 mg/kg with ketamine 3 mg/kg. The medications were prepared and mixed with 25% dextrose up to a maximum volume of 0.3 ml/kg. Result: Uniform and acceptable sedation scores were seen in both the groups, without any serious side effects. However, the combination offered significantly more children in an awake, calm and quiet state, who were easily separated from their parents. The induction scores, Recovery room characteristics and time to achieve satisfactory Aldrete score were also comparable between the two groups. Conclusion: Oral midazolam alone and a combination of midazolam with ketamine provide equally effective anxiolysis and separation characteristics. However, the combination provided more Benefits.en_US
dc.identifier.affiliationsDepartment of Anesthesia, Surat Municipal Institute of Medical Education & Research, Surat, Indiaen_US
dc.identifier.affiliationsDepartment of Anesthesia, Surat Municipal Institute of Medical Education & Research, Surat, Indiaen_US
dc.identifier.citationModi Shreya, Patel Subhash. Comparative Evaluation of Midazolam and Ketamine with Midazolam Alone as Oral Premedication in Children. National Journal of Medical Research . 2023 Jan; 13(1): 13-16en_US
dc.identifier.issn2249-4995
dc.identifier.issn2277-8810
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/217136
dc.languageenen_US
dc.publisherMedsci Publicationsen_US
dc.relation.issuenumber1en_US
dc.relation.volume13en_US
dc.source.urihttps://doi.org/10.55489/njmr.13012023938en_US
dc.subjectMidazolamen_US
dc.subjectketamineen_US
dc.subjectPediatricen_US
dc.subjectpremedicationen_US
dc.titleComparative Evaluation of Midazolam and Ketamine with Midazolam Alone as Oral Premedication in Childrenen_US
dc.typeJournal Articleen_US
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