A study of autologous melanocyte transfer in treatment of stable vitiligo.

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dc.contributor.authorPandya, Vishvabhavanen_US
dc.contributor.authorParmar, Kirti Sen_US
dc.contributor.authorShah, Bela Jen_US
dc.contributor.authorBilimoria, F Een_US
dc.date.accessioned2009-05-28T08:42:37Z
dc.date.available2009-05-28T08:42:37Z
dc.date.issued2005-11-06en_US
dc.description.abstractBACKGROUND: Replenishing melanocytes selectively in vitiliginous macules by autologous melanocytes is a promising treatment. With expertise in culturing melanocytes, it has now become possible to treat larger recipient areas with smaller skin samples. AIM: To study the extent of repigmentation after autologous melanocyte transplantation in patients with stable vitiligo. METHODS: The melanocytes were harvested as an autologous melanocyte rich cell suspension from a donor split thickness graft. Melanocyte culture was performed in selected cases where the melanocyte cell count was insufficient to meet the requirement of the recipient area. These cells were then transplanted to the recipient area that had been superficially dermabraded. RESULTS: An excellent response was seen in 52.17% cases with the autologous melanocyte rich cell suspension (AMRCS) technique and in 50% with the melanocyte culture (MC) technique. CONCLUSION: Autologous melanocyte transplantation can be an effective form of surgical treatment in stable but recalcitrant lesions of vitiligo.en_US
dc.description.affiliationDepartment of Dermatology, Civil Hospital and BJ Medical College, Ahmedabad, India. vbpandya@rediffmail.comen_US
dc.identifier.citationPandya V, Parmar KS, Shah BJ, Bilimoria FE. A study of autologous melanocyte transfer in treatment of stable vitiligo. Indian Journal of Dermatology, Venereology and Leprology. 2005 Nov-Dec; 71(6): 393-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53011
dc.language.isoengen_US
dc.source.urihttps://www.ijdvl.comen_US
dc.subject.meshAdulten_US
dc.subject.meshCell Separation --methodsen_US
dc.subject.meshCells, Cultureden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMelanocytes --transplantationen_US
dc.subject.meshSkin Transplantationen_US
dc.subject.meshTransplantation, Autologousen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVitiligo --surgeryen_US
dc.titleA study of autologous melanocyte transfer in treatment of stable vitiligo.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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