Dyslipidemia: clinical approaches, evaluation of methods and strategies for standardization.

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dc.contributor.authorAhsan, S Ken_US
dc.date.accessioned1997-11-06en_US
dc.date.accessioned2009-05-29T06:18:22Z
dc.date.available1997-11-06en_US
dc.date.available2009-05-29T06:18:22Z
dc.date.issued1997-11-06en_US
dc.description.abstractDisorders in lipid metabolism (dyslipidemia) can result to the chronic heart disease. The low density lipoprotein (LDL) is a critical subfraction of total cholesterol present in serum because it is directly linked to coronary heart disease (CHD). The growing awareness of the risks of CHD stipulates the need for more accurate and precise measurement of LDL cholesterol. Current approaches in diagnosing and monitoring CHD is largely dependent on calculated LDL (CLDL) value due to the inherent complexity of ultracentrifugation method. While friedwald's calculated formula may provide comparable values with ultracentrifugation method, it may provide a result which is different. This difference may be of clinical significance. The lipoprotein electrophoresis may be useful in measuring LDL cholesterol, in the diagnosis of type III hyperlipidemia (broad beta band) and when the triglyceride level exceeds 400 mg/dl. The result that compares the CLDL with that obtained by the electrophoresis showed a significant difference (P > or = 0.000) for LDL and insignificant difference (P = 0.068) for high density lipoprotein (HDL) cholesterol.en_US
dc.description.affiliationDepartment of Pathology, King Faisal University, Dammam, Saudi Arabia.en_US
dc.identifier.citationAhsan SK. Dyslipidemia: clinical approaches, evaluation of methods and strategies for standardization. Indian Journal of Medical Sciences. 1997 Nov; 51(11): 420-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/68656
dc.language.isoengen_US
dc.source.urihttps://www.indianjmedsci.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCholesterol, HDL --analysisen_US
dc.subject.meshCholesterol, LDL --analysisen_US
dc.subject.meshCoronary Disease --epidemiologyen_US
dc.subject.meshElectrophoresis --methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperlipidemias --complicationsen_US
dc.subject.meshLipoproteins, HDL --analysisen_US
dc.subject.meshLipoproteins, LDL --analysisen_US
dc.subject.meshMaleen_US
dc.subject.meshMass Screening --standardsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshTriglycerides --analysisen_US
dc.titleDyslipidemia: clinical approaches, evaluation of methods and strategies for standardization.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
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