Study the usefulness of cartridge based NUCLEIC acid amplification test in bronchoalveolar lavage samples in the diagnosis of smear-negative/non sputum producing patients with suspected tuberculosis

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dc.contributor.authorKumar, K. Rajen_US
dc.contributor.authorReddy, Sonyen_US
dc.contributor.authorVamsi, Raghuen_US
dc.date.accessioned2020-11-18T09:58:01Z
dc.date.available2020-11-18T09:58:01Z
dc.date.issued2019-03
dc.description.abstractBackground: The aim of study is to evaluate the diagnostic value of the CBNAAT in BAL samples of smear negative for AFB or who could not produce an expectorated sputum sample.Methods: A prospective and observational study of in patient and out patient department in Department of Pulmonary Medicine of Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar during the period November 2017 to November 2018.Results: Bronchoalveolar lavage cartridge based nucleic acid amplification test in bronchoalveolar lavage was done for 60 samples of patients who were having history and chest x-ray suggestive of pulmonary tuberculosis with sputum AFB negative. Out of these sputum negative samples 25 were BAL CBNAAT positive and rest were negative.Conclusions: CBNAAT adds significantly to the diagnostic yield of PTB in comparison to sputum smear microscopy. It has additional advantage of identifying rifampicin resistance with high sensitivity and specificity.en_US
dc.identifier.affiliationsDepartment of Pulmonary Medicine, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, Telangana, Indiaen_US
dc.identifier.citationKumar K. Raj, Reddy Sony, Vamsi Raghu. Study the usefulness of cartridge based NUCLEIC acid amplification test in bronchoalveolar lavage samples in the diagnosis of smear-negative/non sputum producing patients with suspected tuberculosis. International Journal of Research in Medical Sciences. 2019 Mar; 7(3): 886-888en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211238
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20190942en_US
dc.subjectAmplification testen_US
dc.subjectBronchoalveolar lavageen_US
dc.subjectPulmonary tuberculosisen_US
dc.subjectSputum negativeen_US
dc.titleStudy the usefulness of cartridge based NUCLEIC acid amplification test in bronchoalveolar lavage samples in the diagnosis of smear-negative/non sputum producing patients with suspected tuberculosisen_US
dc.typeJournal Articleen_US
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