Is it worth treating Category I failure patients with Category II regimen.

dc.contributor.authorSantha, T
dc.contributor.authorGopi, P G
dc.contributor.authorRajeswari, R
dc.contributor.authorSelvakumar, N
dc.contributor.authorSubramani, R
dc.contributor.authorChandrasekaran, V
dc.contributor.authorRani, B
dc.contributor.authorThomas, A
dc.contributor.authorNarayanan, P R
dc.date.accessioned2013-05-29T06:38:25Z
dc.date.available2013-05-29T06:38:25Z
dc.date.issued2005-10
dc.description.abstractBackground: Very little information is available on the drug susceptibility profile among patients who are treated with standardized short-course chemotherapy regimens under programme conditions. Methods: Sputum samples were collected from new sputum smear-positive patients declared ‘failure’ after treatment with Category I regimen under tuberculosis control programme using DOTS strategy from a rural area of Tamil Nadu. Results: Of 1463 patients started on Category I regimen between May1999 and December 2002, 74 cases were declared as ‘failures’ (smear positive at 5/6 months of treatment). We collected sputum samples from 60 (81%) of 74 ‘failures’ and 27% (16 of 60) of them were culture-negative for M tuberculosis and 17% (10 of 60) had organisms resistant to Isoniazid and Rifampicin (MDR TB). Conclusion: Based on the drug susceptibility profile at the time of ‘failure’, treating Category I ‘failures’ with Category II regimen with close monitoring appears to be justified.en_US
dc.identifier.citationSantha T, Gopi P G, Rajeswari R, Selvakumar N, Subramani R, Chandrasekaran V, Rani B, Thomas A, Narayanan P R. Is it worth treating Category I failure patients with Category II regimen. Indian Journal of Tuberculosis. 2005 Oct; 52(4): 203-206.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/146975
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/ibr/t05/i4/ibrt05i4p203.pdfen_US
dc.subjectTuberculosisen_US
dc.subjectDOTSen_US
dc.titleIs it worth treating Category I failure patients with Category II regimen.en_US
dc.typeArticleen_US
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