Efficacy of Phenylephrine in Preventing Hemodynamic Responses of Oxytocin during Elective Cesarean Section:A Randomized,Double-Blind ,Controlled Trial

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dc.contributor.authorMohta, Medhaen_US
dc.contributor.authorKumar, Vijayen_US
dc.contributor.authorAgarwal, Rachnaen_US
dc.contributor.authorChilkoti, Geetanjali T.en_US
dc.contributor.authorDuggal, Sakshien_US
dc.date.accessioned2020-01-02T06:17:11Z
dc.date.available2020-01-02T06:17:11Z
dc.date.issued2019-01
dc.description.abstractThis study compared hemodynamic changes and occurrence of complications following oxytocin administration with a prior injection of phenylephrine 100 μg or normal saline during elective cesarean section. Sixty-six healthy term parturients with uncomplicated, singleton pregnancy undergoing elective cesarean section under spinal anesthesia were studied. They received either intravenous phenylephrine 100 μg or normal saline before oxytocin 3 IU was administered over 30 seconds. Oxytocin dose was repeated depending on the adequacy of uterine tone. There was no significant change in systolic, diastolic, and mean arterial pressures during the initial 3 minutes following oxytocin administration in the phenylephrine group but a significant fall in mean and diastolic pressures in the saline group. Heart rate did not change significantly, and no significant complications occurred in either of the groups. To conclude, phenylephrine 100 µg administered before oxytocin injection maintained hemodynamic parameters better than normal saline injection during elective cesarean sectionen_US
dc.identifier.affiliationsDepartment of Anaesthesiology and Critical Care, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, Indiaen_US
dc.identifier.affiliationsMBBS, MD, MAMS, 28-B, Pocket-C, SFS Flats, Mayur Vihar Phase-III, Delhi 110096, India, medhamohta@gmail.comen_US
dc.identifier.citationMohta Medha, Kumar Vijay, Agarwal Rachna, Chilkoti Geetanjali T., Duggal Sakshi. Efficacy of Phenylephrine in Preventing Hemodynamic Responses of Oxytocin during Elective Cesarean Section:A Randomized,Double-Blind ,Controlled Trial . Annals of the National Academy of Medical Sciences (India). 2019 Jan; 55(1): 48-53en_US
dc.identifier.issn0379-038X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/189735
dc.languageenen_US
dc.publisherNational Academy of Medical Sciences (India)en_US
dc.relation.issuenumber1en_US
dc.relation.volume55en_US
dc.source.urihttps://doi.org/10.1055/s-0039-1694079en_US
dc.titleEfficacy of Phenylephrine in Preventing Hemodynamic Responses of Oxytocin during Elective Cesarean Section:A Randomized,Double-Blind ,Controlled Trialen_US
dc.typeJournal Articleen_US
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