Circumoval precipitin (COP) test using air-dried eggs of Schistosoma japonicum and S. mansoni.

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dc.contributor.authorKamiya, Hen_US
dc.date.accessioned2009-05-27T16:41:09Z
dc.date.available2009-05-27T16:41:09Z
dc.date.issued1983-12-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractIn an attempt to establish a simplified circumoval precipitin (COP) test for the diagnostic purpose of schistosomiasis, air-dried eggs of both Schistosoma japonicum and S. mansoni were tested as antigens for this assay. Twenty-six sera from mice infected with S. japonicum showed positive COP reactions as assessed by air-dried eggs. Among 36 serum samples from patients with schistosomiasis japonica, five exhibited false negative reaction when assessed with air-dried eggs and showed a minimum level of COP reaction when assessed with lyophilized eggs. Similarly, all of 30 serum samples from jirds (Meriones unguiculatus) infected with S. mansoni gave positive COP reaction when assessed using air-dried egg. Diagnostic sensitivity of air-dried egg-system was comparable to those of fresh egg-or lyophilized egg-systems. A simple COP technique employing air-dried eggs, instead of lyophilized or fresh ones, would be thus useful for the serodiagnosis of schistosomiasis in local endemic areas, where sophisticated laboratory facilities are not available.en_US
dc.identifier.citationKamiya H. Circumoval precipitin (COP) test using air-dried eggs of Schistosoma japonicum and S. mansoni. The Southeast Asian Journal of Tropical Medicine and Public Health. 1983 Dec; 14(4): 451-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/35777
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDesiccation --methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGerbillinaeen_US
dc.subject.meshHumansen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred C3Hen_US
dc.subject.meshOvum --immunologyen_US
dc.subject.meshPrecipitin Tests --methodsen_US
dc.subject.meshSchistosoma japonicum --immunologyen_US
dc.subject.meshSchistosoma mansoni --immunologyen_US
dc.subject.meshSchistosomiasis --diagnosisen_US
dc.titleCircumoval precipitin (COP) test using air-dried eggs of Schistosoma japonicum and S. mansoni.en_US
dc.typeJournal Articleen_US
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