Comparative study of renal cell carcinoma in patients less than 40 years of age and older age patients: A retrospective single-center study

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dc.contributor.authorPal, Dilip Kumaren_US
dc.contributor.authorMaurya, Arun Kumaren_US
dc.contributor.authorJana, Debarshien_US
dc.date.accessioned2020-01-02T06:28:02Z
dc.date.available2020-01-02T06:28:02Z
dc.date.issued2018-07
dc.description.abstractBACKGROUND: Renal cell carcinoma (RCC) is typically found in the older age group between 50 and 70 years of age. However, diagnosis of renal cancer is increasing more rapidly in patients less than 40 years if age compared to older age patients. AIMS AND OBJECTIVES: To compare the clinicopathological spectrum and survival in patients with RCC in relation to age in a tertiary care hospital in eastern India. STUDY DESIGN: Retrospective cohort study. MATERIALS AND METHODS: Patients operated between February 2008 and January 2017 for renal masses having clinical and radiological suspicion and histopathologically proven RCC were analyzed from hospital records. Clinicopathological data and survival study were compared between patients less than 40 years of age and older age patients. STATISTICAL ANALYSIS USED: Statistical and survival analysis was done using Statistical Package for the Social Sciences 20. RESULTS: Among 198 patients, 36 (18.2%) patients less than 40 years were diagnosed with RCC and 162 in older patients. In these 36 younger patients, 17 (47.2%) were male and 19 (52.7%) were female. A total of 63.8% in younger age group and 69.1% of older patients were diagnosed with stage 1 and 2 RCC; comparing younger to older patients, younger patients had high number of papillary carcinoma (22.2% vs. 11.7%, P = 0.096). Younger patients have shown marginally better 5-year overall survival and disease-free survival (P > 0.05). CONCLUSION: Our study concludes that younger age patients were more affected by RCC specially papillary RCC, when compared to western population. In addition females had more incidence of RCC. Prognosis was similar in both groups.en_US
dc.identifier.affiliationsDepartment of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationPal Dilip Kumar, Maurya Arun Kumar, Jana Debarshi. Comparative study of renal cell carcinoma in patients less than 40 years of age and older age patients: A retrospective single-center study. Indian Journal of Cancer. 2018 Jul; 55(3): 297-300en_US
dc.identifier.issn0019-509X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190373
dc.languageenen_US
dc.publisherIndian Cancer Societyen_US
dc.relation.issuenumber3en_US
dc.relation.volume55en_US
dc.source.urihttps://dx.doi.org//10.4103/ijc.IJC_636_17en_US
dc.titleComparative study of renal cell carcinoma in patients less than 40 years of age and older age patients: A retrospective single-center studyen_US
dc.typeJournal Articleen_US
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