Platelet functions & lipid profile within 24 hours following an attack of TIA, thrombotic & haemorrhagic stroke.

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dc.contributor.authorGaur, S Pen_US
dc.contributor.authorGarg, R Ken_US
dc.contributor.authorAgarwal, Sen_US
dc.contributor.authorKar, A Men_US
dc.contributor.authorSrimal, R Cen_US
dc.date.accessioned1994-06-01en_US
dc.date.accessioned2009-05-27T08:36:37Z
dc.date.available1994-06-01en_US
dc.date.available2009-05-27T08:36:37Z
dc.date.issued1994-06-01en_US
dc.description.abstractThe present study was undertaken to evaluate comparatively the lipid profile and platelet functions within 24 h of the three most frequent types of stroke encountered in clinical practice. Twenty patients of transient ischaemic attacks, 22 of thrombotic stroke and 26 of haemorrhagic stroke (hypertensive putaminal haemorrhage), all within 24 h of the acute event, and 21 control subjects were studied. Spontaneous platelet aggregation, platelet aggregation induced with adenosine diphosphate (2.5, 3.75 and 5.0 microM) and lipid profile (serum cholesterol, triglycerides, high density lipoprotein, low density lipoprotein and very low density lipoprotein) estimations were performed in all the subjects. Mean platelet aggregation values were significantly lower in haemorrhagic stroke patients as compared to controls. Serum cholesterol, triglycerides and very low density lipoprotein levels in ischaemic groups i.e., transient ischaemic attacks and thrombotic stroke patients, were significantly elevated, more so in the former group. It appears that platelet hypofunction has a role in the pathogenesis of hypertensive putaminal haemorrhage while in patients of transient ischaemic attack and thrombotic stroke, lipids may be a contributing factor in cerebral atherogenesis.en_US
dc.description.affiliationDivision of Clinical & Experimental Medicine, Central Drug Research Institute, K.G. Medical College, Lucknow.en_US
dc.identifier.citationGaur SP, Garg RK, Agarwal S, Kar AM, Srimal RC. Platelet functions & lipid profile within 24 hours following an attack of TIA, thrombotic & haemorrhagic stroke. Indian Journal of Medical Research. 1994 Jun; 99(): 259-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/25041
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBlood Platelets --physiologyen_US
dc.subject.meshCerebral Hemorrhage --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIntracranial Embolism and Thrombosis --blooden_US
dc.subject.meshIschemic Attack, Transient --blooden_US
dc.subject.meshLipids --blooden_US
dc.subject.meshLipoproteins --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTime Factorsen_US
dc.titlePlatelet functions & lipid profile within 24 hours following an attack of TIA, thrombotic & haemorrhagic stroke.en_US
dc.typeJournal Articleen_US
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