Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn leaves in alloxan-induced diabetic rats.
| dc.contributor.author | Maniyar, Yasmeen | |
| dc.contributor.author | Bhixavatimath, Prabhu | |
| dc.date.accessioned | 2016-02-17T03:31:49Z | |
| dc.date.available | 2016-02-17T03:31:49Z | |
| dc.date.issued | 2012-04 | |
| dc.description.abstract | Background: India is considered as the diabetic capital of the world. The study of plants having antihyperglycemic and hypolipidemic activities may give a new approach in the treatment of diabetes mellitus. Objective: The study was intended to evaluate the antihyperglycemic and hypolipidemic activity of aqueous extract of leaves of Carica papaya Linn. (AECPL) in alloxan-induced diabetic albino rats. Materials and Methods: Diabetes was induced in albino rats by administration of alloxan monohydrate (120 mg/kg, i.p.). Rats were divided into 6 groups of 6 animals each. First group served as non-diabetic control, second group as diabetic control, third group as standard and was treated with 0.1 mg/kg/day of glibenclamide. Group 4, 5, and 6 received 100, 200, and 400 mg/kg body weight of AECPL. Blood samples were analyzed for blood glucose on day 0, 1, 7, 14, 21 and lipid profi le on day 21. Results: The AECPL showed signifi cant reduction (P<0.01) in blood glucose level and serum lipid profi le levels with 400 mg/kg body weight in alloxan-induced diabetic rats as compared with the control. Conclusion: It is concluded that AECPL is effective in controlling blood glucose levels and in improving lipid profi le in diabetic rats. | en_US |
| dc.identifier.citation | Maniyar Yasmeen, Bhixavatimath Prabhu. Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn leaves in alloxan-induced diabetic rats.Journal of Ayurveda and Integrative Medicine. 2012 Apr-June; 3(2): 70-74. | en_US |
| dc.identifier.issn | 0975-9476 | |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/173113 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.jaim.in/article.asp?issn=0975-9476;year=2012;volume=3;issue=2;spage=70;epage=74;aulast=Maniyar | en_US |
| dc.subject | Aqueous leaf extract | en_US |
| dc.subject | hypoglycemia | en_US |
| dc.subject | hypolipidemia | en_US |
| dc.subject | Carica papaya Linn | en_US |
| dc.title | Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn leaves in alloxan-induced diabetic rats. | en_US |
| dc.type | Article | en_US |