Prevalence of Shigella species and their antimicrobial resistance patterns in Eastern Nepal.

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dc.contributor.authorBhattacharya, Shyamalen_US
dc.contributor.authorKhanal, Basudhaen_US
dc.contributor.authorBhattarai, Narayan Ren_US
dc.contributor.authorDas, Murari Len_US
dc.date.accessioned2005-12-08en_US
dc.date.accessioned2009-05-27T03:49:58Z
dc.date.available2005-12-08en_US
dc.date.available2009-05-27T03:49:58Z
dc.date.issued2005-12-08en_US
dc.descriptionJournal of Health, Population, and Nutrition.en_US
dc.description.abstractThe study was conducted to determine the prevalence of Shigella species and their antimicrobial resistance patterns in eastern Nepal. Stool samples submitted to the diagnostic laboratory of B.P. Koirala Institute of Health Sciences, Nepal, during August 2000-July 2004, were cultured for Shigella species and were confirmed by biochemical and serological tests. Of 53 Shigella species isolated, Shigella dysenteriae type 1 was the most predominant isolate (73.7%), followed by S. flexneri (23%) and S. boydii (4%). The majority (79%) of Shigella species were isolated from children aged less than five years. An overall high resistance was observed for trimethoprim-sulphamethoxazole, ampicillin, nalidixic acid, mecillinam, and ciprofloxacin. There was a statistically significant (p < 0.001) increasing trend in the prevalence of ciprofloxacin resistance in S. dysenteriae type 1. The results suggest reconsideration of the empiric use of these antimicrobial agents for shigellosis. A further study is required to evaluate additional antimicrobial agents.en_US
dc.description.affiliationDepartment of Microbiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. bhattacharyas2000@yahoo.comen_US
dc.identifier.citationBhattacharya S, Khanal B, Bhattarai NR, Das ML. Prevalence of Shigella species and their antimicrobial resistance patterns in Eastern Nepal. Journal of Health, Population, and Nutrition. 2005 Dec; 23(4): 339-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/791
dc.language.isoengen_US
dc.source.urihttps://www.icddrb.org/pub/publication.jsp?classificationID=30&typeClassificationID=2en_US
dc.source.urihttps://www.icddrb.org/publication.cfm?classificationID=30&pubID=6639en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDrug Resistance, Bacterial --physiologyen_US
dc.subject.meshDysentery, Bacillary --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshNepal --epidemiologyen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshShigella --isolation & purificationen_US
dc.titlePrevalence of Shigella species and their antimicrobial resistance patterns in Eastern Nepal.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, U.S. Gov't, Non-P.H.S.en_US
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