Pattern of inheritance in three sudden unexplained death syndrome ("Lai-tai") families.

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dc.contributor.authorSangwatanaroj, Sen_US
dc.contributor.authorNgamchareon, Cen_US
dc.contributor.authorPrechawat, Sen_US
dc.date.accessioned2009-05-27T18:10:29Z
dc.date.available2009-05-27T18:10:29Z
dc.date.issued2001-06-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractSudden Unexplained Death Syndrome (SUDS) (or Lai-tai) is sudden death in previously healthy young adults without any structural cause of death from autopsy findings. Our previous data showed that familial SUDS is not X-linked recessive. The objective of this study was to determine the pattern of inheritance in familial SUDS using the ECG markers of Brugada syndrome (RBBB and ST-segment elevation in V1 to V3), SUDS and presumptive SUDS as phenotypes. We employed the standard 12-lead ECG and higher intercostal space (ICS) V1 to V3 (-V1 to -V3 and -2V1 to -2V3) leads ECG in SUDS relatives after procainamide and drew the pedigree. We studied 62 relatives of 9 SUDS victims who died in Singapore and selected 3 families (n = 34) for the procainamide test and ECG. The mean age was 36.4 +/- 23.6 years (4-78 years). Three SUDS families showed the same pattern of inheritance of autosomal dominant.en_US
dc.description.affiliationDepartment of Medicine, Faculty of Medicine, Chulalongkom University, Bangkok, Thailand.en_US
dc.identifier.citationSangwatanaroj S, Ngamchareon C, Prechawat S. Pattern of inheritance in three sudden unexplained death syndrome ("Lai-tai") families. Journal of the Medical Association of Thailand. 2001 Jun; 84 Suppl 1(): S443-51en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38608
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAutopsyen_US
dc.subject.meshCause of Deathen_US
dc.subject.meshDeath, Sudden --ethnologyen_US
dc.subject.meshDeath, Sudden, Cardiac --ethnologyen_US
dc.subject.meshElectrocardiographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGenetic Predisposition to Disease --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshPedigreeen_US
dc.subject.meshRegistriesen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshThailand --epidemiologyen_US
dc.titlePattern of inheritance in three sudden unexplained death syndrome ("Lai-tai") families.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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