Naturally occurring anti-native DNA antibodies in SLE binding Z-DNA.
dc.contributor.author | Sehgal, V | en_US |
dc.contributor.author | Ali, R | en_US |
dc.date.accessioned | 1990-06-01 | en_US |
dc.date.accessioned | 2009-05-27T07:36:37Z | |
dc.date.available | 1990-06-01 | en_US |
dc.date.available | 2009-05-27T07:36:37Z | |
dc.date.issued | 1990-06-01 | en_US |
dc.description.abstract | A high degree of specificity of circulating anti-DNA antibody for double stranded DNA in the sera of SLE patients was found, as compared to single stranded polymer. The antibody recognized brominated DNA, a polymer that appears to attain Z-conformation as indicated on the basis of UV absorption characteristics. The existence in native DNA of regions undergoing B----Z transition has been detected. | en_US |
dc.description.affiliation | Department of Biochemistry, Faculty of Medicine, Aligarh Muslim University. | en_US |
dc.identifier.citation | Sehgal V, Ali R. Naturally occurring anti-native DNA antibodies in SLE binding Z-DNA. Indian Journal of Medical Research. 1990 Jun; 92(): 158-62 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/21380 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://icmr.nic.in/ijmr/ijmr.htm | en_US |
dc.subject.mesh | Antibody Specificity | en_US |
dc.subject.mesh | Autoantibodies --blood | en_US |
dc.subject.mesh | DNA --immunology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Lupus Erythematosus, Systemic --immunology | en_US |
dc.subject.mesh | Nucleic Acid Conformation | en_US |
dc.title | Naturally occurring anti-native DNA antibodies in SLE binding Z-DNA. | en_US |
dc.type | Journal Article | en_US |
dc.type | Research Support, Non-U.S. Gov't | en_US |
Files
License bundle
1 - 1 of 1