Orally active insulin mimics: where do we stand now?

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dc.contributor.authorBalasubramanyam, Men_US
dc.contributor.authorMohan, Ven_US
dc.date.accessioned2001-09-25en_US
dc.date.accessioned2009-06-01T14:25:00Z
dc.date.available2001-09-25en_US
dc.date.available2009-06-01T14:25:00Z
dc.date.issued2001-09-25en_US
dc.description70 references.en_US
dc.description.abstractThe war against diabetes through the development of new drugs is an ongoing continuous process to counter the alarming global increase in the prevalence of diabetes and its complications, particularly in developing countries like India. Unfortunately, the speed with which our knowledge of diabetes and its effects is expanding is not matched by the availability of new drugs. Following the identification of the insulin receptor (IR), its intrinsic kinase activity and molecular cloning, many studies have looked at IR as an ideal drug target. This review summarizes in brief the latest advancements in this field with particular reference to the current situation in respect of the development of orally active insulin mimetics in the treatment of type 2 diabetes.en_US
dc.description.affiliationMadras Diabetes Research Foundation (MDRF), 35 Conran Smith Road, Gopalapuram, Chennai 600 086, India. mvdsc@vsnl.comen_US
dc.identifier.citationBalasubramanyam M, Mohan V. Orally active insulin mimics: where do we stand now? Journal of Biosciences. 2001 Sep; 26(3): 383-90en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/110812
dc.language.isoengen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/index.htmlen_US
dc.subject.mesh1-Phosphatidylinositol 3-Kinase --metabolismen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDiabetes Mellitus --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulin --administration & dosageen_US
dc.subject.meshMembrane Proteins --metabolismen_US
dc.subject.meshModels, Biologicalen_US
dc.subject.meshProtein Tyrosine Phosphatases --metabolismen_US
dc.subject.meshReceptor, Insulin --metabolismen_US
dc.subject.meshSignal Transduction --physiologyen_US
dc.subject.meshVanadium --metabolismen_US
dc.titleOrally active insulin mimics: where do we stand now?en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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