Infective endocarditis in hypertrophic cardiomyopathy--mural and aortic valve vegetations: a case report.

dc.contributor.authorPachirat, Orathaien_US
dc.contributor.authorKlungboonkrong, Viraten_US
dc.contributor.authorTantisirin, Cherdchaien_US
dc.date.accessioned2009-05-27T19:11:15Z
dc.date.available2009-05-27T19:11:15Z
dc.date.issued2006-04-16en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractHypertrophic cardiomyopathy (HCM) is infrequently complicated by infective endocarditis (IE). The authors report the case of a 46-year-old woman developing IE in asymptomatic HCM. Blood cultures were positive for Streptococcus viridans. Echocardiography demonstrated: 1) a mobile (1.2 x 1 cm2) vegetation attached to the septal endocardium at the site of contact between the mitral valve leaflet and the hypertrophic septum; 2) two large (2.7 x 1.7 cm2 and 1.6 x 1.1 cm2) vegetations at NCC and RCC respectively of aortic valve, causing moderate valve regurgitation, and, 3) a mural (1 x 0.8 cm2) vegetation on the posterior wall of the left ventricle. On the third day of hospitalization, the patient underwent aortic valve replacement and removal of the vegetations. Antibiotics were continued for another four weeks. The patient recovered and follow-up was uneventful. Thus, chronic endocardial trauma of the septum, a common finding in HCM with outflow tract obstruction, may provide a fertile nidus for the development of vegetation, which in turn would play the major role in the pathogenesis of IE.en_US
dc.description.affiliationCardiovascular Disease Division, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Orathai@hotmail.comen_US
dc.identifier.citationPachirat O, Klungboonkrong V, Tantisirin C. Infective endocarditis in hypertrophic cardiomyopathy--mural and aortic valve vegetations: a case report. Journal of the Medical Association of Thailand. 2006 Apr; 89(4): 522-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/40639
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAortic Valve --pathologyen_US
dc.subject.meshCardiomyopathy, Hypertrophic --complicationsen_US
dc.subject.meshEndocarditis, Bacterial --etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Valve Diseases --physiopathologyen_US
dc.subject.meshHeart Valve Prosthesis Implantationen_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshViridans Streptococci --isolation & purificationen_US
dc.titleInfective endocarditis in hypertrophic cardiomyopathy--mural and aortic valve vegetations: a case report.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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