Dilatation of radiation-induced esophageal strictures under sublingual buprenorphine analgesia: a pilot study.

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dc.contributor.authorDesai, D Cen_US
dc.contributor.authorWagle, S Den_US
dc.contributor.authorMohandas, K Men_US
dc.contributor.authorSwaroop, V Sen_US
dc.date.accessioned1997-01-01en_US
dc.date.accessioned2009-05-29T03:30:28Z
dc.date.available1997-01-01en_US
dc.date.available2009-05-29T03:30:28Z
dc.date.issued1997-01-01en_US
dc.description.abstractBACKGROUND: Pain during dilatation of radiation strictures is a troublesome complaint. There is little information on sedation and analgesia during this procedure. We performed a pilot study to compare the analgesic efficacy of sublingual buprenorphine and intravenous pentazocine during dilatation of radiation-induced esophageal strictures. METHODS: Thirty-one patients with esophageal cancer who had radiation-induced strictures were randomized to receive either buprenorphine 0.2 mg sublingually two hours before dilatation (n = 17) or pentazocine 30 mg intravenously five minutes before dilatation (n = 14). Dilatation was considered successful if it could be performed to 12 mm diameter or more. Pain experienced during dilatation was graded as mild, moderate or severe. RESULTS: Sixteen patients in the buprenorphine group and 12 in the pentazocine group were dilated to > 12 mm size (p = ns). Twelve and nine patients respectively in the two groups experienced mild or no pain; ten and six patients had minor side-effects (p = ns). CONCLUSION: Buprenorphine is useful for sedoanalgesia during dilatation of radiation-induced strictures of the esophagus.en_US
dc.description.affiliationDivision of Gastroenterology, Tata Memorial Hospital, Mumbai.en_US
dc.identifier.citationDesai DC, Wagle SD, Mohandas KM, Swaroop VS. Dilatation of radiation-induced esophageal strictures under sublingual buprenorphine analgesia: a pilot study. Indian Journal of Gastroenterology. 1997 Jan; 16(1): 14-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/65420
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdministration, Sublingualen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnalgesics, Opioid --administration & dosageen_US
dc.subject.meshAnesthesia, Local --methodsen_US
dc.subject.meshBalloon Dilatation --methodsen_US
dc.subject.meshBuprenorphine --administration & dosageen_US
dc.subject.meshEsophageal Neoplasms --radiotherapyen_US
dc.subject.meshEsophageal Stenosis --etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInjections, Intravenousen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPentazocine --administration & dosageen_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRadiation Injuries --complicationsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleDilatation of radiation-induced esophageal strictures under sublingual buprenorphine analgesia: a pilot study.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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