Etiopathogenesis of cataract: An appraisal.
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Date
2014-02
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Abstract
Natural eye lens is a crystalline substance to produce a clear passage for light. Cataract is opacity within
the clear lens of the eye and is the dominant cause of socio‑medical problem i.e., blindness worldwide.
The only available treatment of cataract is surgery. However, insufficient surgical facilities in poor and
developing countries and post‑operative complications inspire researchers to find out other modes of
treatment for cataract. In this review, an attempt has been made to appraise various etiological factors of
cataract to make their perception clear to build up counterpart treatment. Present study is an assortment
of various available literatures and electronic information in view of cataract etiopathogenesis. Various
risk factors have been identified in development of cataracts. They can be classified in to genetic factors,
ageing (systemic diseases, nutritional and trace metals deficiencies, smoking, oxidative stress etc.),
traumatic, complicated (inflammatory and degenerative diseases of eye), metabolic (diabetes, galactosemia
etc.), toxic substances including drugs abuses, alcohol etc., radiation (ultraviolet, electromagnetic waves etc.)
are implicated as significant risk factors in the development of cataract.
Description
Keywords
Blindness, cataract, eye lens, risk factors, treatment of cataract
Citation
Gupta Varun B, Rajagopala Manjusha, Ravishankar Basavaiah. Etiopathogenesis of cataract: An appraisal. Indian Journal of Ophthalmology. 2014 Feb ; 62 (2): 102-110.