Molecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran.

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dc.contributor.authorAfkari, Rouhi
dc.contributor.authorPirouzi, Aliyar
dc.contributor.authorMohsenzadeh, Mehdi
dc.contributor.authorAzadi, Mohammad
dc.contributor.authorJafari, Mohammad
dc.date.accessioned2013-03-15T09:38:58Z
dc.date.available2013-03-15T09:38:58Z
dc.date.issued2012-10
dc.description.abstractBackground: SEN virus (SEN-V) and TT virus (TTV) have been classified in the circoviridae family. Both are single-stranded, non-enveloped DNA viruses of about 3800 nucleotides. Patients on maintenance hemodialysis (HD) have a high risk of blood-borne viral infections. SEN-V and TTV has been reported from a number of HD units from various countries throughout the world. Materials and Methods: A total of 377 blood samples obtained from 150 healthy donors and 227 HD patients were collected at the HD center. SEN-V and TTV DNA was determined by polymerase chain reaction (PCR) in all samples. Results: TTV was detected in 109 (48.01%) of 227 hemodialysed patients and 14 (9.33%) of 150 voluntary blood donors (significant, P < 0.05). The PCR results for SEN-V-D/H DNA showed that 65 (28.63%) were positive for SEN-V-D and 33 (14.53%) were positive for SEN-V-H. 9.69% of 227 patients were positive for SEN-V-D/H co-infection. In the control group, SEN-V-D was detected in 14 (9.33%) and SEN-V-H was detected in 15 (10%) of the 150 (100%) blood donors. Conclusion: These findings show that the prevalence of SEN-V-D/H and TTV is higher than healthy blood donors. Also, these results indicate that the prevalence of SEN-V and TTV infections in our region is similar with that in other countries.en_US
dc.identifier.citationAfkari Rouhi, Pirouzi Aliyar, Mohsenzadeh Mehdi, Azadi Mohammad, Jafari Mohammad. Molecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran. Indian Journal of Pathology & Microbiology. 2012 Oct-Dec 55(4): 478-480.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/145640
dc.language.isoenen_US
dc.source.urihttps://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=478;epage=480;aulast=Afkarien_US
dc.subjectBlood donorsen_US
dc.subjecthemodialysisen_US
dc.subjectSEN-V infectionen_US
dc.subjectTT virusen_US
dc.subject.meshBlood Donors
dc.subject.meshDNA Virus Infections --blood
dc.subject.meshDNA Virus Infections --diagnosis
dc.subject.meshDNA Virus Infections --epidemiology
dc.subject.meshDNA Virus Infections --isolation & purification
dc.subject.meshHumans
dc.subject.meshIran --epidemiology
dc.subject.meshPatients
dc.subject.meshRenal Dialysis --utilization
dc.subject.meshTorque teno virus --isolation & purification
dc.titleMolecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran.en_US
dc.typeArticleen_US
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