Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America.

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dc.contributor.authorEnas, E Aen_US
dc.contributor.authorGarg, Aen_US
dc.contributor.authorDavidson, M Aen_US
dc.contributor.authorNair, V Men_US
dc.contributor.authorHuet, B Aen_US
dc.contributor.authorYusuf, Sen_US
dc.date.accessioned1996-07-01en_US
dc.date.accessioned2009-05-27T04:22:00Z
dc.date.available1996-07-01en_US
dc.date.available2009-05-27T04:22:00Z
dc.date.issued1996-07-01en_US
dc.description.abstractThe prevalence of coronary heart disease (CHD) and its risk factors in first-generation Asian Indian immigrants to the United States of America (US) were compared with those of the native Caucasian population. A total of 1688 Asian Indian physicians and their family members (1131 men and 557 women, age > or = 20 years) completed a questionnaire and in 580 subjects serum lipoproteins were determined. The age-adjusted prevalence of myocardial infarction and/or angina was approximately three times more in Asian Indian men compared to the Framingham Offspring Study (7.2% versus 2.5%; P < 0.0001) but was similar in women (0.3% versus 1%; p = 0.64). Asian Indians had higher prevalence of noninsulin-dependent diabetes mellitus (NIDDM; 7.6% versus 1%; p < 0.0001) but markedly lower prevalence of cigarette smoking (1.3% versus 27%; p < 0.0001) and obesity (4.2% versus 22%; p < 0.0001). Hypertension was less prevalent in Asian Indian men 14.2% versus 19.1%, p < 0.008) but similar in women (11.3% versus 11.4%). The prevalence of elevated total a low-density lipoprotein (LDL) cholesterol levels was similar in men [17% versus 23.4% (p = 0.24) and 13.7% versus 22.3% (p = 0.22), respectively] but lower in women [15% versus 26.1% (p = 0.018) and 14.3% versus 19.6% (p = 0.047) respectively]. The mean levels of high-density lipoprotein (HDL) cholesterol were less in younger (30-39 years) Asian Indian men (mean: 0.98 versus 1.18 mmol/l; p < 0.001) and middle-aged (30-59 years) women (mean: 1.24 versus 1.45 mmol/l; p < 0.001). The prevalence of hypertriglyceridaemia was similar in men (18.5% versus 11.3%), but higher in Asian Indian women (8.3% versus 4.1%, p = 0.02). To conclude, immigrant Asian Indian men to the US have high prevalence of CHD, NIDDM, low HDL cholesterol levels and hypertriglyceridaemia. All these have "insulin resistance" as a common pathogenetic mechanism and seem to be the most important risk factors.en_US
dc.description.affiliationAmerican Association of Physicians from India, University of Texas Southwestern Medical Center at Dallas 75235-9052, USA.en_US
dc.identifier.citationEnas EA, Garg A, Davidson MA, Nair VM, Huet BA, Yusuf S. Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America. Indian Heart Journal. 1996 Jul-Aug; 48(4): 343-53en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/4163
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAgeden_US
dc.subject.meshCoronary Disease --blooden_US
dc.subject.meshEmigration and Immigrationen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --ethnologyen_US
dc.subject.meshLipids --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSex Factorsen_US
dc.subject.meshUnited States --epidemiologyen_US
dc.titleCoronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
dc.typeResearch Support, U.S. Gov't, P.H.S.en_US
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