Study of Predictors for Ventilatory Support in Patients of Organophosphorus Compound Poisoning

Simple item page
dc.contributor.authorThakur, Vipinsinghen_US
dc.contributor.authorBiradar, S.Men_US
dc.date.accessioned2020-01-02T06:12:16Z
dc.date.available2020-01-02T06:12:16Z
dc.date.issued2019-01
dc.description.abstractOrganophosphorus compound poisoning is used most commonly for suicidal attempts which is seen frequently in farmers of younger age group of lower socio-economic status from rural areas. The aim of study is to know the clinical profile of organophosphate compound poisoning and to identify the factors which help in predicting the need for ventilatory support in this poisoning. Methods: A hospital based prospective cross sectional study was conducted with 100 patients to analyze the clinical profile of organophosphate compound poisoning and identify the factors which help in predicting the need for ventilatory support in organophosphorous compound poisoning. Results: Majority of the patients were in the age group of 21-30 years. The mean age of the patients was 31.96 ± 14.12 years. The route of exposure was oral in all the patients. The most common organophosphorus compound consumed in our study was Malathion (28%) ,46 (46%) patients had very poor GCS score (≤7), 38 (38%) patients had low serum cholinesterase levels (≤2100 IU/L),9 (9%) patients had amylase levels>140 U/L, 43 (43%) patients required ventilatory support while 57 (57%) patients did not require ventilator support. Among patients with fasciculations 64% were on ventilatory support. There was significant association of fasciculations and ventilatory support. 87 (87%) patients survived while 13 (13%) patients died in our study. All patients that died were on ventilatory support. Conclusion: Clinical and biochemical parameters such as greater the time lag from consumption of OP poison till getting specific treatment, Lower GCS scoring, Generalized Fasciculation’s, Low cholinesterase levels were strong predictors for the need for Assisted Ventilation in OP poisoning.en_US
dc.identifier.affiliationsJunior Resident, Department of Medicine, BLDE University, Sri B M Patil Medical College Hospital and Research Centre, Vijayapur-586103, Karnataka, India.en_US
dc.identifier.affiliationsAssociate Professor, Department of Medicine, B.L.D.E University, Sri B M Patil Medical College Hospital and Research Centre, Vijayapur586103, Karnataka, India.en_US
dc.identifier.citationThakur Vipinsingh, Biradar S.M. Study of Predictors for Ventilatory Support in Patients of Organophosphorus Compound Poisoning. Annals of International medical and Dental Research. 2019 Jan; 5(1): 23-29en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/189321
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber1en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2019.5.1.ME6en_US
dc.subjectOrganophosphorusen_US
dc.subjectpoisoningen_US
dc.subjectventilationen_US
dc.titleStudy of Predictors for Ventilatory Support in Patients of Organophosphorus Compound Poisoningen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
aimdr2019v5n1p23.pdf
Size:
853.64 KB
Format:
Adobe Portable Document Format
Download
Collections
Annals of International Medical and Dental Research