Risk factors in the transmission of leptospiral infection.

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dc.contributor.authorMurhekar, M Ven_US
dc.contributor.authorSugunan, A Pen_US
dc.contributor.authorVijayachari, Pen_US
dc.contributor.authorSharma, Sen_US
dc.contributor.authorSehgal, S Cen_US
dc.date.accessioned1998-05-22en_US
dc.date.accessioned2009-05-27T08:47:03Z
dc.date.available1998-05-22en_US
dc.date.available2009-05-27T08:47:03Z
dc.date.issued1998-05-22en_US
dc.description.abstractAn unmatched case control study was conducted to study the various risk factors for acquiring leptospiral infection in Diglipur tehsil of North Andaman. A random sample of 1014 persons residing in various villages of Diglipur was inducted into the study. Serum samples were collected from them and tested for anti-leptospiral antibodies using microscopic agglutination test (MAT) using Leptospira grippotyphosa, L. australis, L. canicola and L. icterohaemorrhagiae antigens. Persons with a titre of 1:50 or more were considered as the cases (550) and the seronegatives as controls (464). Information about 30 variables relating to household characteristics, occupation, contact with animals and behavioural factors was collected by interviewing the subjects. The prevalences of these variables in both the groups were calculated and the odds ratio with 95 per cent confidence intervals were computed. The seroprevalence rate was found to increase linearly with age and it was significantly higher in males. None of the risk factors studied had any association with seropositivity to serovar L. icterohaemorrhagiae. For the other serovars, some form of recent exposure to outdoor environment had significant association. Other factors which had association with infection with specific serovars included use of well or stream water and presence of dogs in the house for infection with L. grippotyphosa, farming families and presence of cattle in the houses for infection with L. australis and the habit of bathing in ponds for infection with L. canicola. These observed associations can be taken as clues of the transmission cycles and would help in guiding further investigations for understanding the epidemiology of leptospirosis in these islands.en_US
dc.description.affiliationRegional Medical Research Centre (ICMR), Port Blair.en_US
dc.identifier.citationMurhekar MV, Sugunan AP, Vijayachari P, Sharma S, Sehgal SC. Risk factors in the transmission of leptospiral infection. Indian Journal of Medical Research. 1998 May; 107(): 218-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/25624
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCattleen_US
dc.subject.meshDogsen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLeptospira --isolation & purificationen_US
dc.subject.meshLeptospirosis --epidemiologyen_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSex Factorsen_US
dc.titleRisk factors in the transmission of leptospiral infection.en_US
dc.typeJournal Articleen_US
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