Childhood onset myasthenia gravis.

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dc.contributor.authorRaksadawan, Natteen_US
dc.contributor.authorKankirawatana, Pongkiaten_US
dc.contributor.authorBalankura, Kampanaden_US
dc.contributor.authorPrateepratana, Patcharinen_US
dc.contributor.authorSangruchi, Tumtipen_US
dc.contributor.authorAtchaneeyasakul, La-Ongsrien_US
dc.date.accessioned2009-05-27T18:07:59Z
dc.date.available2009-05-27T18:07:59Z
dc.date.issued2002-08-31en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe authors share experiences in taking care of 27 cases of childhood onset myasthenia gravis (MGS). In all cases, the diagnosis was confirmed by a combination of clinical examination and Neostigmine test. The majority (92%) had localized ocular myasthenia with median onset of symptoms at 33 months of age. About 24 per cent of them progressed to generalized MGS. A few (8%) presented with respiratory failure that required ventilatory support with onset of symptoms at about 22 months. Thymectomy was performed in 10 cases. Complete and partial remissions were achieved in about 70 per cent and 26 per cent of cases respectively with the combination of an immunosuppressant (azathioprine) and a Cholinesterase inhibitor (pyridostigmine). None experienced a myasthenic crisis with proper management and good follow-up using the above combinations.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationRaksadawan N, Kankirawatana P, Balankura K, Prateepratana P, Sangruchi T, Atchaneeyasakul LO. Childhood onset myasthenia gravis. Journal of the Medical Association of Thailand. 2002 Aug; 85 Suppl 2(): S769-77en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38522
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAge of Onseten_US
dc.subject.meshAzathioprine --administration & dosageen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshMyasthenia Gravis --diagnosisen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshSteroids --administration & dosageen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshThymectomy --methodsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleChildhood onset myasthenia gravis.en_US
dc.typeJournal Articleen_US
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