Yeast colonisation & fungaemia in preterm neonates in a tertiary care centre.

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dc.contributor.authorSingh, Ken_US
dc.contributor.authorChakrabarti, Aen_US
dc.contributor.authorNarang, Aen_US
dc.contributor.authorGopalan, Sen_US
dc.date.accessioned1999-11-19en_US
dc.date.accessioned2009-05-27T07:05:16Z
dc.date.available1999-11-19en_US
dc.date.available2009-05-27T07:05:16Z
dc.date.issued1999-11-19en_US
dc.description.abstractSeventy consecutive preterm neonates who stayed in the hospital for more than seven days between March and October 1996, were studied for colonisation at oral, umbilical, groin, and rectal areas and for fungaemia. Overall, 71.4 per cent of the neonates were colonised and colonisation occurred within 24 h in 38 per cent preterm neonates. Neonates weighing less than 1500 g were colonised more frequently at more than one site and had higher load of yeast. Candida albicans (19%), Pichia (Hansenula) anomala (17.5%), C. tropicalis (13.2%), C. parapsilosis (12.3%) and Trichosporon cutaneum (10.0%) were the predominant colonising yeasts. Fungaemia was detected in 22.8 per cent of preterm neonates with predominance of P. anomala fungaemia (62.5%). Prematurity, male sex, broad spectrum antibiotic therapy, intubation and higher colonising rate were identified as significant risk factors for development of fungaemia. Except one strain of C. tropicalis, all yeast strains were sensitive to commonly used systemic antifungal agents. Study highlights the importance of routine surveillance of yeast colonisation of preterm neonates with identifying possible risk factors.en_US
dc.description.affiliationDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh.en_US
dc.identifier.citationSingh K, Chakrabarti A, Narang A, Gopalan S. Yeast colonisation & fungaemia in preterm neonates in a tertiary care centre. Indian Journal of Medical Research. 1999 Nov; 110(): 169-73en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19244
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnti-Bacterial Agents --adverse effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFungemia --classificationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Prematureen_US
dc.subject.meshMaleen_US
dc.subject.meshMouth --microbiologyen_US
dc.subject.meshMycoses --classificationen_US
dc.subject.meshRectum --microbiologyen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshUmbilicus --microbiologyen_US
dc.subject.meshYeasts --classificationen_US
dc.titleYeast colonisation & fungaemia in preterm neonates in a tertiary care centre.en_US
dc.typeJournal Articleen_US
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