Correlation of autonomic indices with thyroid status.

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dc.contributor.authorGautam, Sujataen_US
dc.contributor.authorTandon, O Pen_US
dc.contributor.authorAwashi, Ren_US
dc.contributor.authorSekhri, Ten_US
dc.contributor.authorSircar, S Sen_US
dc.date.accessioned2003-04-17en_US
dc.date.accessioned2009-06-01T04:53:06Z
dc.date.available2003-04-17en_US
dc.date.available2009-06-01T04:53:06Z
dc.date.issued2003-04-17en_US
dc.description.abstractThe autonomic status in female thyroid patients was compared with healthy, age matched normal females taken as controls. The patients (29 +/- 7 years) were categorised into two groups: hyperthyroid and hypothyroid. The valsalva manoeuvre, standing to lying ratio (S/L ratio) and immediate heart rate response to standing (30:15 ratio) to assess the parasympathetic status while the galvanic skin response (GSR) was recorded to assess the sympathetic status. Statistical analysis was done using Student's t-test for comparing between the different groups and regression analysis were performed between autonomic indices and thyroid hormone levels. Although the mean values were not significantly different in hypothyroid and hyperthyroid patients, yet the correlation between autonomic function and thyroid hormone levels indicates a statistically significant difference (P-value<0.05), with the S/L ratio. The correlation was negative for log [T3] and log [T4], while it was positive for log [TSH]. This indicates that there is decreased parasympathetic activity with increased T3 and T4, which is in agreement earlier reports. The GSR, which is one of the measures of sympathetic activity, was found to be unaffected.en_US
dc.description.affiliationDepartment of Physiology, University College of Medical Sciences, G.T.B. Hospital, Shahdra, Delhi.en_US
dc.identifier.citationGautam S, Tandon OP, Awashi R, Sekhri T, Sircar SS. Correlation of autonomic indices with thyroid status. Indian Journal of Physiology and Pharmacology. 2003 Apr; 47(2): 164-70en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/106181
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAutonomic Nervous System --physiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Rate --physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperthyroidism --blooden_US
dc.subject.meshHypothyroidism --blooden_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshThyroxine --blooden_US
dc.subject.meshTriiodothyronine --blooden_US
dc.subject.meshValsalva Maneuver --physiologyen_US
dc.titleCorrelation of autonomic indices with thyroid status.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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