A study to evaluate asbestos fiber burden in lung and pleural malignancies.

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dc.contributor.authorVerma, S K
dc.contributor.authorSrivastava, Rahul
dc.contributor.authorKant, Surya
dc.contributor.authorPrasad, R
dc.contributor.authorGarg, R
dc.contributor.authorAhmad, Iqbal
dc.contributor.authorHusain, Nuzhat
dc.date.accessioned2013-03-11T08:24:30Z
dc.date.available2013-03-11T08:24:30Z
dc.date.issued2010-07
dc.description.abstractBackground: There is scarcity of data on asbestos fiber burden in lung and pleural malignancies. Aim: To evaluate asbestos fiber burden in biopsy samples of suspected lung and pleural malignancies. Study Design: This was a single-centre, observational study. Study Period: From August 2010 to July 2010. Setting: Department of Pulmonary Medicine, CSMMU, UP, Lucknow, a tertiary care hospital in India. Study Population: Suspected cases of lung and pleural malignancy. Materials and Methods: Biopsy tissues taken by computed tomography (CT)-guided biopsy, bronchoscopic biopsy, and pleural biopsy by Cope's needle were analyzed for histopathology and asbestos burden by Haq et al.'s method. Results: 20 patients were studied. Mean fiber burden was 9.25 × 10 4 fibers/g. Average burden in lung malignancies (11 patients) was 9.178 × 10 4 fibers/g and in pleural tissue (9 patients) was 9.332 × 10 4fibers/g. Among the different cell types, mean fiber burden in squamous cell carcinoma was 8.99 × 10 4 fibers/g, in adenocarcinoma was 9.71 × 10 4 fibers/g, and in small cell carcinoma was 7.54 × 10 4 fibers/g. Mean fiber burden in bronchoscopic endobronchial biopsy tissue was 10.69 × 10 4 fibers/g, while in CT-guided biopsy was 8.60× 10 4fibers/g. Conclusion: Maximum number of fibers was found in adenocarcinoma.en_US
dc.identifier.citationVerma S K, Srivastava Rahul, Kant Surya, Prasad R, Garg R, Ahmad Iqbal, Husain Nuzhat. A study to evaluate asbestos fiber burden in lung and pleural malignancies. Indian Journal of Medical Sciences. 2010 July; 64(7) 315-319.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/145545
dc.language.isoenen_US
dc.source.urihttps://www.indianjmedsci.org/article.asp?issn=0019-5359;year=2010;volume=64;issue=7;spage=315;epage=319;aulast=Vermaen_US
dc.subjectAsbestosen_US
dc.subjectlung canceren_US
dc.subjectbiopsyen_US
dc.subject.meshAdenocarcinoma --chemically induced
dc.subject.meshAdenocarcinoma --epidemiology
dc.subject.meshAsbestos --analysis
dc.subject.meshAsbestos --isolation & purification
dc.subject.meshBiopsy --methods
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshImage-Guided Biopsy --methods
dc.subject.meshLung Neoplasms --chemically induced
dc.subject.meshLung Neoplasms --diagnosis
dc.subject.meshPatients
dc.subject.meshPleural Neoplasms --chemically induced
dc.subject.meshPleural Neoplasms --epidemiology
dc.subject.meshTertiary Care Centers
dc.subject.meshTomography, X-Ray Computed
dc.titleA study to evaluate asbestos fiber burden in lung and pleural malignancies.en_US
dc.typeArticleen_US
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