Chimeric Fusion Karyotypes in Childhood B-cell Acute Lymphoblastic Leukemia.
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Date
2014-02
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Abstract
Cytogenetics study using combination of conventional
cytogenetics and fluorescent insitu hybridization was carried
out in 171 pediatric acute lymphoblastic leukemia patients
subgrouped to B-ALL (n=126) and T-ALL (n=45) by bone
marrow morphology and immunophenotype. The chromosomal
aberration frequency in B-ALL and T-ALL was 79% and 71%,
respectively. TEL/AML1 translocation was detected in 28% of
patients.
Description
Keywords
Complex chromosomal change, FISH, Gemsa, banded karyotype, Translocations
Citation
Kerketta Lily S, Rao Vundinti Babu, Ghosh Kanjaksha .Chimeric Fusion Karyotypes in Childhood B-cell Acute Lymphoblastic Leukemia. Indian Pediatrics. 2014 February; 51(2): 152-153.