Investigations in the virological etiology in acute retinal inflammation.

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dc.contributor.authorMadhavan, H Nen_US
dc.contributor.authorBiswas, Jen_US
dc.contributor.authorGopal, Len_US
dc.contributor.authorSharma, Ten_US
dc.date.accessioned1995-06-01en_US
dc.date.accessioned2009-05-27T07:02:47Z
dc.date.available1995-06-01en_US
dc.date.available2009-05-27T07:02:47Z
dc.date.issued1995-06-01en_US
dc.description.abstractVirological investigations for herpes simplex virus (HSV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) were performed in nine patients of acute retinal inflammation. Serum samples of all the patients were assayed for IgG and IgM antibodies to HSV, CMV and EBV. Vitreous fluid (VF) from 5 patients was tested by immunofluorescence and culture for detection of HSV and CMV. In four patients, VF was also assayed for IgG and IgM antibodies to HSV and CMV. HSV was shown to be the etiological agent in 3 patients with acute retinal necrosis (ARN) syndrome and in one patient with multifocal retinitis. CMV was the causative agent in one patient of ARN and 1 patient with clinically diagnosed CMV retinitis. Evidences of infection with these three viral agents could not be obtained in one patient with clinical diagnosis of CMV retinitis who tested positive for antibody to human immunodeficiency virus 1. All other patients were HIV negative. Identification of the causative viral agent of acute retinal inflammations may help an ophthalmologist to institute specific therapy particularly for HSV and CMV infections.en_US
dc.description.affiliationVision Research Foundation, Medical Research Foundation, Sankara Nethralaya, Madras.en_US
dc.identifier.citationMadhavan HN, Biswas J, Gopal L, Sharma T. Investigations in the virological etiology in acute retinal inflammation. Indian Journal of Medical Research. 1995 Jun; 101(): 233-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19065
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAntibodies, Viral --analysisen_US
dc.subject.meshCytomegalovirus Retinitis --diagnosisen_US
dc.subject.meshEye Infections, Viral --virologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorescent Antibody Techniqueen_US
dc.subject.meshHerpesviridae Infections --diagnosisen_US
dc.subject.meshHerpesvirus 4, Human --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshKeratitis, Herpetic --diagnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetinitis --virologyen_US
dc.subject.meshVitreous Body --virologyen_US
dc.titleInvestigations in the virological etiology in acute retinal inflammation.en_US
dc.typeJournal Articleen_US
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