Cytohistopathological and ImmunohistochemicalCorrelation of Soft Tissue Lesions

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dc.contributor.authorDash, Ashok Kumaren_US
dc.contributor.authorTripathy, Milanen_US
dc.contributor.authorMohanty, Shushrutaen_US
dc.contributor.authorTripathy, Kiranen_US
dc.contributor.authorNanda, Saurav Narayanen_US
dc.contributor.authorMishra, Debi Prasaden_US
dc.date.accessioned2020-09-24T07:25:37Z
dc.date.available2020-09-24T07:25:37Z
dc.date.issued2019-07
dc.description.abstractIntroduction: In the present era, FNAC has proved to be anessential primary diagnostic procedure for soft tissue lesions.To correlate its efficacy and to further subtype,histopathological examination is done aided by IHC if required.The present study aimed to evaluate the epidemiologicaldistribution of soft tissue lesions with reference to age, sex andsite and to assess the utility of FNAC in terms of sensitivity,specificity, positive and negative predictive values, and overallhistological correlation percentage of cytology in diagnosingvarious types of soft tissue lesions.Materials and Methods: Prospective study was carried outduring the period of Sept 2017 to May 2019 for FNAexamination of soft tissue lesions. Cytopathological andhistopathological examination was carried out in all cases withimmunostaining done in few cases.Results: Of 463 soft tissue lesions that could be successfullyfollowed up, 347 were benign lesions and rest were malignant.Most common age group affected were 31-40 years with slightmale preponderance (M:F=1.37:1). Most common site beingLower extremities. Lipomas were the most common soft tissuelesions (169 cases) and spindle cell sarcomas were the mostcommon malignant lesions. The cytological andhistopathological diagnosis correlated well in almost all casesexcept discordance was seen in 5 cases. The sensitivity andspecificity of the procedure were 97.4% and 99.4%respectively.Conclusion: FNAC was found to be a highly specific andsensitive tool in diagnosing soft tissue lesions and can be fairlyimplemented as it is well tolerated and cost effective forpatients.en_US
dc.identifier.affiliationsAssociate Professor, Department of Pathology, M.K.C.G Medical College and Hospital, Behrampur, Odisha, India.en_US
dc.identifier.affiliationsPG Resident, Department of Pathology, M.K.C.G Medical College and Hospital, Behrampur, Odisha, India.en_US
dc.identifier.affiliationsSenior Resident, Department of Pathology, M.K.C.G Medical College and Hospital, Behrampur, Odisha, India.en_US
dc.identifier.affiliationsMD Pathology, IMS &SUM Hospital ,Bhubaneswar, Odisha, India.en_US
dc.identifier.affiliationsSenior Resident, Department of Orthopaedics, AIIMS, Bhubaneswar, Odisha, Indiaen_US
dc.identifier.affiliationsProfessor & Head, M.K.C.G Medical College and Hospital, Behrampur, Odisha, Indiaen_US
dc.identifier.citationDash Ashok Kumar, Tripathy Milan, Mohanty Shushruta, Tripathy Kiran, Nanda Saurav Narayan, Mishra Debi Prasad. Cytohistopathological and ImmunohistochemicalCorrelation of Soft Tissue Lesions. International Journal of Medical Research Professionals. 2019 Jul; 5(4): 81-88en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203404
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org//10.21276/ijmrp.2019.5.4.019en_US
dc.subjectFNACen_US
dc.subjectSoft Tissue Lesionsen_US
dc.subjectHistopathologyen_US
dc.subjectImmunostainingen_US
dc.titleCytohistopathological and ImmunohistochemicalCorrelation of Soft Tissue Lesionsen_US
dc.typeJournal Articleen_US
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