Analysis of indigenous plasmid sequences of A. baumannii DS002 reveals the existence of lateral mobility and extensive genetic recombination among Acinetobacter plasmids

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dc.contributor.authorSamantarrai, Devyanien_US
dc.contributor.authorYakkala, Harshitaen_US
dc.contributor.authorSiddavattam, Dayanandaen_US
dc.date.accessioned2020-11-18T10:21:05Z
dc.date.available2020-11-18T10:21:05Z
dc.date.issued2020-09
dc.description.abstractGenome sequence of Acinetobacter baumannii DS002 revealed the existence of seven contigs with features of indigenous plasmids. Of the seven contigs, three of them have shown size and sequence identity. They appeared to have been generated due to the unique recombination events leading to a large-scale recombination and sequence inversions. The rest of the indigenous plasmids have shown significant size variations and contained the genetic repertoire required for the detoxification of formaldehyde and biosynthesis of exopolysaccharides. Genetic modules encoding novel toxin–antitoxin systems were found in most of the plasmids to ensure their survival in the host. In some instances, the toxin and antitoxin coding sequences were found on two different plasmids promoting the cosegregation of these two plasmids into the daughter cellsen_US
dc.identifier.affiliationsDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad 500 046, Indiaen_US
dc.identifier.citationSamantarrai Devyani, Yakkala Harshita, Siddavattam Dayananda. Analysis of indigenous plasmid sequences of A. baumannii DS002 reveals the existence of lateral mobility and extensive genetic recombination among Acinetobacter plasmids. Journal of Genetics. 2020 Sep; 99: 1-11en_US
dc.identifier.issn0022-1333
dc.identifier.issn0973-7731
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215489
dc.languageenen_US
dc.publisherIndian Academy of Sciencesen_US
dc.relation.volume99en_US
dc.source.urihttps://doi.org/10.1007/s12041-020-01232-8en_US
dc.subjecthorizontal gene transferen_US
dc.subjectplasmid incompatibilityen_US
dc.subjectAcinetobacter sp. mobile genetic elementsen_US
dc.subjectgene sharing network.en_US
dc.titleAnalysis of indigenous plasmid sequences of A. baumannii DS002 reveals the existence of lateral mobility and extensive genetic recombination among Acinetobacter plasmidsen_US
dc.typeJournal Articleen_US
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