Elevated levels of anti-proteus antibodies in patients with active rheumatoid arthritis.

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dc.contributor.authorWanchu, Aen_US
dc.contributor.authorDeodhar, S Den_US
dc.contributor.authorSharma, Men_US
dc.contributor.authorGupta, Ven_US
dc.contributor.authorBambery, Pen_US
dc.contributor.authorSud, Aen_US
dc.date.accessioned1997-01-01en_US
dc.date.accessioned2009-05-27T08:49:00Z
dc.date.available1997-01-01en_US
dc.date.available2009-05-27T08:49:00Z
dc.date.issued1997-01-01en_US
dc.description.abstractWe carried out this study to determine if our patient population with rheumatoid arthritis (RA) has elevated levels of antibodies to gut bacteria. Seventy patients with RA were categorised as being either active or inactive on clinical grounds. Antibodies to the H and O antigens of Proteus mirabilis and Salmonella typhi were determined by tube agglutination method in these patients, 18 patients with osteoarthritis and 82 healthy controls. There was no significant difference in the anti-proteus antibody titres between both the control groups and patients with inactive disease. However, antibody levels among patients with active disease were significantly higher than controls (P < 0.001). There was no significant difference in anti-salmonella antibody titres among the various disease and control groups. Elevated antibody levels could suggest a role for Proteus as an etiological agent in RA.en_US
dc.description.affiliationDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh.en_US
dc.identifier.citationWanchu A, Deodhar SD, Sharma M, Gupta V, Bambery P, Sud A. Elevated levels of anti-proteus antibodies in patients with active rheumatoid arthritis. Indian Journal of Medical Research. 1997 Jan; 105(): 39-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/25734
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdulten_US
dc.subject.meshAntibodies, Bacterial --blooden_US
dc.subject.meshArthritis, Rheumatoid --immunologyen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProteus mirabilis --immunologyen_US
dc.subject.meshSalmonella typhi --immunologyen_US
dc.titleElevated levels of anti-proteus antibodies in patients with active rheumatoid arthritis.en_US
dc.typeJournal Articleen_US
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