Hemodynamic Response and Dose Requirement during Induction and Intubation with Propofol and Pentothal Sodium in Patients Undergoing Elective Coronary Artery Bypass Surgery

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dc.contributor.authorGore, Mangesh S.en_US
dc.contributor.authorBaliarsingh, Lipika A.en_US
dc.contributor.authorTeckchandani, Deepikaen_US
dc.date.accessioned2020-09-24T07:10:01Z
dc.date.available2020-09-24T07:10:01Z
dc.date.issued2019-05
dc.description.abstractIntroduction: The aim of the study was to observehaemodynamic changes during induction of patientsundergoing CABG with Propofol and Pentothal. It was alsointended to see if fixed dose combination of premedicationwith midazolam and fentanyl helps to reduce dose requirementof induction agents.Material Methods: 60 ASA grade II patients posted forelective Coronary Artery Bypass Surgery (CABG) weredivided into two groups. Group I (propofol group) and groupII (pentothal Group). All patients received premedication asInj.Midazolam 0.03 mg/kg and Inj.Fentanyl 4 µg/kg. Withcomputer generated randomization patient was allotted toeither propofol or Pentothal group. End point of inductiontaken as loss of eye-lash reflex or apnoea whichever appearsfirst. Hemodynamic parameters were recorded from baselinetill 7 minutes post intubation.Results: In both the groups SBP, DPB, MAP, HR and RPPwere found to be comparable. Both the drugs showed stablehemodynamic at various levels of observations. The meandose required for induction was found to be 1.7 mg/kg withpropofol and 1.07 mg/kg with Pentothal.Conclusion: Both propofol and Pentothal are equally ableto provide required stability even when standard doses ofbenzodiazepines and opioids are used in much lower dosesthan mentioned in literatureen_US
dc.identifier.affiliationsAssociate Professor, Department of Anesthesiology, T.N. Medical College & B.Y.L. Nair Ch. Hospital, Mumbaien_US
dc.identifier.affiliationsProfessor, Depatment of Anesthesiology, T.N. Medical College & B.Y.L. Nair Ch. Hospital, Mumbaien_US
dc.identifier.affiliationsEx-Resident, T.N. Medical College & B.Y.L. Nair Ch. Hospital, Mumbai, Indiaen_US
dc.identifier.citationGore Mangesh S., Baliarsingh Lipika A., Teckchandani Deepika. Comparison of Epidural Levo Bupivacaine (0.5%) with Racemic Bupivacaine (0.5%) for Lower Abdominal Surgery. International Journal of Contemporary Medical Research . 2019 May; 6(5): e19-e24en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/202364
dc.languageenen_US
dc.publisherInternational Society for Contemporary Medical Researchen_US
dc.relation.issuenumber5en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.21276/ijcmr.2019.6.5.36en_US
dc.subjectHemodynamic Responseen_US
dc.subjectInductionen_US
dc.subjectIntubationen_US
dc.subjectCoronary Artery Bypass Surgeryen_US
dc.subjectReduction in Doses of Induction Agentsen_US
dc.titleHemodynamic Response and Dose Requirement during Induction and Intubation with Propofol and Pentothal Sodium in Patients Undergoing Elective Coronary Artery Bypass Surgeryen_US
dc.typeJournal Articleen_US
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