An understanding of the genetic basis of asthma.

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dc.contributor.authorBijanzadeh, Mahdi
dc.contributor.authorMahesh, Padukudru A
dc.contributor.authorRamachandra, Nallur B
dc.date.accessioned2011-12-08T04:10:34Z
dc.date.available2011-12-08T04:10:34Z
dc.date.issued2011-08
dc.description.abstractAsthma is the most common chronic childhood disease in developed nations and its prevalence has increased in the world over the last 25 years. It is a complex disease with both genetic and environmental risk factors. Asthma is caused by multiple interacting genes, some having a protective effect and others contributing to the disease pathogenesis, with each gene having its own tendency to be influenced by the environment. This article reviews the current state of the genetics of asthma in six categories, viz. epidemiology, management, aetiology, family and twin studies, segregation and linkage studies, and candidate genes and single nucleotide polymorphisms (SNPs).en_US
dc.identifier.citationBijanzadeh Mahdi, Mahesh Padukudru A, Ramachandra Nallur B. An understanding of the genetic basis of asthma. Indian Journal of Medical Research. 2011 Aug; 134(2): 149-161.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/135742
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181014/en_US
dc.subjectAetiologyen_US
dc.subjectasthmaen_US
dc.subjectlinkageen_US
dc.subjectprevalenceen_US
dc.subjectSNPsen_US
dc.subject.meshAsthma --epidemiology
dc.subject.meshAsthma --genetics
dc.subject.meshCausality
dc.subject.meshDiseases in Twins --genetics
dc.subject.meshGene-Environment Interaction
dc.subject.meshGenetic Linkage --genetics
dc.subject.meshGenetic Predisposition to Disease --genetics
dc.subject.meshHumans
dc.subject.meshPolymorphism, Single Nucleotide --genetics
dc.subject.meshPrevalence
dc.titleAn understanding of the genetic basis of asthma.en_US
dc.typeArticleen_US
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