Extracorporeal Shockwave Therapy in Cardiology: Current Status and Future Perspectives.
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Date
2011
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Abstract
Management of end-stage coronary artery disease is often hopeless because of lack of evidence-based,
uniformly effective, safe, and inexpensive treatment options. Gene- or stem-cell-based therapies are
not yet ready for routine clinical use, and heart transplantation is seriously limited by the scarcity
of organs. In this regard, extracorporeal shockwave therapy is emerging as a noninvasive means to
treat refractory angina and heart failure. Shockwaves are a form of acoustic wave having very high
amplitude, abrupt peaking and very short duration, capable of inducing neovascularization. A
number of preclinical and clinical studies are in favour of its efficacy and safety. However, more
robust evidence is needed before routine application is recommended. Larger, randomized, placebocontrolled
trials will hopefully define its status in the armamentarium of mankind in the battle
against the deadly disease in future.
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Keywords
Shockwave, angiogenesis, angina
Citation
Islam A K M Monwarul, Majumder A A S. Extracorporeal Shockwave Therapy in Cardiology: Current Status and Future Perspectives. Cardiovascular Journal. 2011; 4(1): 80-87.