Equine rabies immunoglobulin: a study on its clinical safety.

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dc.contributor.authorSatpathy, D Men_US
dc.contributor.authorSahu, Ten_US
dc.contributor.authorBehera, T Ren_US
dc.date.accessioned2005-04-22en_US
dc.date.accessioned2009-05-31T12:48:23Z
dc.date.available2005-04-22en_US
dc.date.available2009-05-31T12:48:23Z
dc.date.issued2005-04-22en_US
dc.description.abstractTo confirm and assess the clinical safety of equine rabies immunoglobulin (ERIG) administered locally for postexposure prophylaxis against rabies since human rabies immunoglobulin is too expensive to be affordable by most patients, a study was carried out among 3723 patients who attended the antirabies clinic, department of community medicine, MKCG Medical College Hospital, an urban tertiary hospital between September 1, 2003 and March 31, 2004. They were advised ERIG, 1621 patients were of high risk due to the nature of the bites or animal, but only 286 patients of them who could afford the treatment received it. Side-effects were monitored during the follow-up visits on days 3,7,14,30,60 and 90. Statistical analysis was done by using simple proportions and chi-square test. Of the 286 cases receiving antirabies treatment, 214 patients had dog bites and in 100 cases the animal showed abnormal behaviour. Pain (n=237) was the most common side-effect and in 18 patients fever was the systemic side-effect. No anaphylaxis was noted in the study. On day 90 none of the patients had developed rabies. So it can be concluded that ERIG is safe for passive immunisation against rabies.en_US
dc.description.affiliationDepartment of Community Medicine, MKCG Medical College, Brahmapur.en_US
dc.identifier.citationSatpathy DM, Sahu T, Behera TR. Equine rabies immunoglobulin: a study on its clinical safety. Journal of the Indian Medical Association. 2005 Apr; 103(4): 238, 241-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/101353
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshFemaleen_US
dc.subject.meshHorsesen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulins --therapeutic useen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRabies --epidemiologyen_US
dc.subject.meshRabies Vaccinesen_US
dc.subject.meshRabies virus --immunologyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleEquine rabies immunoglobulin: a study on its clinical safety.en_US
dc.typeJournal Articleen_US
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