Perinatal Transmission and Outcomes of SARS-CoV-2 Infection

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Date
2022-11
Journal Title
Journal ISSN
Volume Title
Publisher
Dr. K C Chaudhuri Foundation
Abstract
Maternal SARS-CoV-2 infection can adversely afect the birth and neonatal outcomes. The authors prospectively enrolled 196 neonates born to 193 SARS-CoV-2–positive mothers to determine the rate of mother-to-baby transmission of SARSCoV-2 and its efect on short-term neonatal outcomes in Indian population. Nineteen babies turned out to be RT-PCR– positive for SARS-CoV-2, carrying a perinatal transmission rate of 9.8%. Rates of prematurity and low birth weight were 12.8% and 18.9% in the neonatal group, respectively. On comparing SARS-CoV-2–positive (n=19) and negative (n=177) neonatal groups, rate of prematurity, hospital admission rate, and death rate were higher in the former group. The placental positivity rate for SARS-CoV-2 was 8.1%, but no relation was found between placental and neonatal infection.
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Keywords
SARS-CoV-2, Perinatal transmission, Neonatal outcomes, Placental infection
Citation
Kumar Charan, Soni J. P., Goyal Vishnu Kumar, Nag Vijaya Lakshmi, Rathore Pradeep Singh, Sharma Akash. Perinatal Transmission and Outcomes of SARS-CoV-2 Infection. Indian Journal of Pediatrics. 2022 Nov; 89(11): 1123–1125