Vibrio cholerae resistant to 2,4-diamino-6,7-diisopropylpteridine (O/129) isolated from patients with enteritis in Ceará, Brazil.

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dc.contributor.authorHofer, Een_US
dc.contributor.authorReis, E Men_US
dc.contributor.authorQuintaes, B Ren_US
dc.contributor.authorRodrigues, D Pen_US
dc.contributor.authorFeitosa, I Sen_US
dc.contributor.authorAngelo, M Ren_US
dc.contributor.authorRibeiro, L Hen_US
dc.date.accessioned2001-03-08en_US
dc.date.accessioned2009-05-27T03:50:15Z
dc.date.available2001-03-08en_US
dc.date.available2009-05-27T03:50:15Z
dc.date.issued2001-03-08en_US
dc.descriptionJournal of Health, Population, and Nutrition.en_US
dc.description.abstractThis paper reports the characterization of clinical Vibrio cholerae resistant to vibriostatic agent O/129, using classical and plasmid analysis. In a study conducted during December 1991-September 1993, two of 7,058 V. cholerae strains, obtained from patients suspected to have cholera in the State of Ceará, northeast Brazil, were resistant to 150 micrograms of the vibriostatic agent O/129 (2,4-diamino-6,7-diisopropylpteridine). One strain was identified as V. cholerae O1 El Tor Inaba and the other one as serogroup O22. Only one O1 strain harboured a plasmid of 147 kb transferable to Escherichia coli K12, and five strains of V. cholerae O1 and non-O1 were sensitive to O/129 and plasmid-negative at a frequency between 8 x 10(-2) and 3.6 x 10(-5). Additionally, O/129-resistant strains of V. cholerae O1 and O22 were resistant to trimethoprim/sulphamethoxazole.en_US
dc.description.affiliationDepartamento de Bacteriologia Instituto Oswaldo Cruz FIOCRUZ Av. Brasil, 4365 Rio de Janeiro RJ 21045-900 Brazil. dalia@ioc.fiocruz.bren_US
dc.identifier.citationHofer E, Reis EM, Quintaes BR, Rodrigues DP, Feitosa IS, Angelo MR, Ribeiro LH. Vibrio cholerae resistant to 2,4-diamino-6,7-diisopropylpteridine (O/129) isolated from patients with enteritis in Ceará, Brazil. Journal of Health, Population, and Nutrition. 2001 Mar; 19(1): 39-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/947
dc.language.isoengen_US
dc.source.urihttps://www.icddrb.org/pub/publication.jsp?classificationID=30&typeClassificationID=2en_US
dc.source.urihttps://www.icddrb.org/publication.cfm?classificationID=30&pubID=362en_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshBrazilen_US
dc.subject.meshCholera --microbiologyen_US
dc.subject.meshDrug Resistance, Microbialen_US
dc.subject.meshEnteritis --microbiologyen_US
dc.subject.meshFeces --microbiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshPteridines --pharmacologyen_US
dc.subject.meshVibrio cholerae --drug effectsen_US
dc.titleVibrio cholerae resistant to 2,4-diamino-6,7-diisopropylpteridine (O/129) isolated from patients with enteritis in Ceará, Brazil.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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