Dengue infection with central nervous system manifestations.

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dc.contributor.authorThisyakorn, Uen_US
dc.contributor.authorThisyakorn, Cen_US
dc.contributor.authorLimpitikul, Wen_US
dc.contributor.authorNisalak, Aen_US
dc.date.accessioned2009-05-27T15:41:36Z
dc.date.available2009-05-27T15:41:36Z
dc.date.issued1999-09-25en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractA prospective observational study was conducted over a seven years period to determine the clinical and laboratory findings of dengue patients with central nervous system manifestations. Thirty serologically confirmed dengue infected patients with central nervous system manifestations were seen at the Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok and at Songkhla Hospital, Songkhla, Thailand. The age ranged between 3 months and 14 years with a mean age of 6.2 years. Seventeen were boys and thirteen were girls. The central nervous system manifestations included alteration of consciousness 76.7%, seizures 63.3%, pyramidal tract signs 36.7%, meningeal signs 30% and headache 26.7%. Eleven patients had primary while 19 had secondary dengue infection. Cerebrospinal fluid examination showed lymphocytic pleocytosis in 6 out of 28 patients while presence of anti-dengue IgM antibodies was detected in 2 out of 19 specimens of cerebrospinal fluid tested. Two patients died, autopsy was done on one patient and examination of the brain was compatible with viral encephalitis.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationThisyakorn U, Thisyakorn C, Limpitikul W, Nisalak A. Dengue infection with central nervous system manifestations. The Southeast Asian Journal of Tropical Medicine and Public Health. 1999 Sep; 30(3): 504-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33425
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshCentral Nervous System Viral Diseases --complicationsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDengue --complicationsen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulin M --cerebrospinal fluiden_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshProspective Studiesen_US
dc.titleDengue infection with central nervous system manifestations.en_US
dc.typeJournal Articleen_US
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