CRISPR/Cas9-mediated Editing of Human β-globin Gene in Human Cells: A Commentary on the Research Ethics.
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Date
2015
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Abstract
Abstract: Recently, Chinese researchers published the results of their research using a gene-editing technology
on abnormal human zygotes. The research team believes this research has prospective clinical application, viz.,
for gene therapy for β-thalassemia, a white blood cell disorder, and plan to persist with further studies, despite
technical problems in this experiment. The research has elicited international criticism from both scientific and
bioethics domains, because it innovates beyond the current global consensus against human germ line
modification. This paper comments on some ethical issues presented by the research report and concludes that,
under present circumstances, the Chinese research team did not meet a standard of scientific responsibility.
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Keywords
CRISPR/Cas9, human germ line modification, ethics, China, gene-editing technology
Citation
Swazo Norman K. CRISPR/Cas9-mediated Editing of Human β-globin Gene in Human Cells: A Commentary on the Research Ethics. Bangladesh Journal of Bioethics 2015 Vol.6 (1):22-26.