Sero-prevalence of unvaccinated adolescent girls susceptible to rubella virus infection seen in a tertiary care hospital of Patna, Bihar, India

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dc.contributor.authorPrasad, Dipalien_US
dc.contributor.authorPrasad, Nidhien_US
dc.contributor.authorPrakash, Vidyuten_US
dc.contributor.authorParveen, Sadiaen_US
dc.contributor.authorMishra, Urvashien_US
dc.date.accessioned2020-10-16T08:04:35Z
dc.date.available2020-10-16T08:04:35Z
dc.date.issued2020-05
dc.description.abstractBackground: Rubella infection occurring during early pregnancy results in congenital rubella syndrome (CRS).  WHO estimates that worldwide more than 100,000 children are born with CRS each year and most of them are in the developing countries. For assessing population immunity against rubella, sero-surveys are generally recommended among adolescent girls and reproductive age female. In India, sero-surveys conducted by different authors have indicated that about 10-30% of adolescent females are susceptible to rubella infection. Adolescent girls are selected because they are at a critical stage of child bearing age and their immunity against Rubella infection is the particular area of interest. objective of this study was to estimate the sero-prevalence of unvaccinated adolescent girls susceptible to Rubella virus infection attending a tertiary care hospital of Patna and then accordingly counsel for vaccination.Methods: A total 150 adolescent girls in the age group of 10-19 years who had not received MMR vaccine were included in the study. Serum IgG antibody titer for rubella was estimated by the ELISA method.Results: A total 65.33% of the adolescent girls were found to be rubella seropositive and (34.67%) were seronegative. The urban adolescent girls had a higher seropositivity of 85.2% as compared to rural adolescent girls.Conclusions: The study indicates that a substantial number of adolescents (34.67%) are seronegative and hence susceptible to rubella infection.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, IGIMS, Patna, Bihar, Indiaen_US
dc.identifier.affiliationsDepartment of Virology, IGIMS, Patna, Bihar, Indiaen_US
dc.identifier.citationPrasad Dipali, Prasad Nidhi, Prakash Vidyut, Parveen Sadia, Mishra Urvashi. Sero-prevalence of unvaccinated adolescent girls susceptible to rubella virus infection seen in a tertiary care hospital of Patna, Bihar, India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2020 May; 9(5): 1972-1975en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207675
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20201790en_US
dc.subjectAdolescent girlsen_US
dc.subjectCongenital rubella syndromeen_US
dc.subjectRubella susceptibleen_US
dc.subjectSeroprevalenceen_US
dc.subjectVaccinationen_US
dc.titleSero-prevalence of unvaccinated adolescent girls susceptible to rubella virus infection seen in a tertiary care hospital of Patna, Bihar, Indiaen_US
dc.typeJournal Articleen_US
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