Neurotrophic Keratitis in Locally Advanced Nasopharyngeal Carcinoma.

Simple item page
dc.contributor.authorNayak, MAen_US
dc.contributor.authorBhat, Sen_US
dc.contributor.authorKamath, BSen_US
dc.contributor.authorCharlotte, Aen_US
dc.date.accessioned2025-08-13T10:00:10Z
dc.date.available2025-08-13T10:00:10Z
dc.date.issued2025-03
dc.description.abstractNasopharyngeal carcinoma is a locally invasive malignant tumor that invades the orbit frequently. We came across a 65-year-old man with locally advanced nasopharyngeal carcinoma on chemotherapy with orbital invasion causing total ophthalmoplegia, loss of corneal sensations, and ptosis. He also had a central neurotrophic keratitis with hypopyon. Based on these findings, a diagnosis of left-sided superior orbital fissure syndrome with neurotrophic keratitis was made. CT scan of the head revealed a soft-tissue mass abutting the superior aspect of the orbit and cavernous sinus and tumor recurrence was confirmed. We started the patient on topical fortified antibiotics and Atropine after placing a bandage contact lens. He was advised palliative radiotherapy by the medical oncologist. In two months, there was marked improvement in ocular motility, ptosis, and redness. The ulcer had healed by the formation of a central macular opacity. Corneal sensations had returned. This case exemplifies the reversible nature of superior orbital fissure syndrome and associated corneal anesthesia. As the tumor is radiosensitive, the mass effect of the tumor was reduced leading to the resolution of ophthalmoplegia and healing of the ulcer.en_US
dc.identifier.affiliationsDepartment of Ophthalmology, Father Muller Medical College, Mangaluru, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Father Muller Medical College, Mangaluru, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Father Muller Medical College, Mangaluru, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Father Muller Medical College, Mangaluru, Indiaen_US
dc.identifier.citationNayak MA, Bhat S, Kamath BS, Charlotte A. Neurotrophic Keratitis in Locally Advanced Nasopharyngeal Carcinoma.. Online Journal of Health and Allied Sciences. 2025 Mar; 24(93): 1-2en_US
dc.identifier.issn0972-5997
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/252874
dc.languageenen_US
dc.publisherLight House Polyclinicen_US
dc.relation.issuenumber93en_US
dc.relation.volume24en_US
dc.source.urihttps://www.ojhas.org/issue93/2025-1-10.pdfen_US
dc.subjectNeurotrophic keratitisen_US
dc.subjectNasopharyngeal carcinomaen_US
dc.subjectSuperior orbital fissure syndromeen_US
dc.titleNeurotrophic Keratitis in Locally Advanced Nasopharyngeal Carcinoma.en_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ojhas2025v24n93p1i.pdf
Size:
218.88 KB
Format:
Adobe Portable Document Format
Download
Collections
Online Journal of Health and Allied Sciences