Lymphatic filariasis caused by Brugia malayi in an endemic area of Narathiwat Province, southern of Thailand.

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dc.contributor.authorTriteeraprapab, Sen_US
dc.contributor.authorKarnjanopas, Ken_US
dc.contributor.authorPorksakorn, Cen_US
dc.contributor.authorSai-Ngam, Aen_US
dc.contributor.authorYentakam, Sen_US
dc.contributor.authorLoymak, Sen_US
dc.date.accessioned2009-05-27T20:44:15Z
dc.date.available2009-05-27T20:44:15Z
dc.date.issued2001-06-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractLymphatic filariasis caused by Brugia malayi is highly prevalent in Narathiwat province of Thailand. The World Health Organization has aimed to eliminate the disease globally by the year 2020. To achieve the goal, assessment of the real disease situation should be integrated as part of the control program. The preliminary data for long-term study of the disease situation in this endemic area is necessary for the elimination program of lymphatic filariasis. By using the conventional microscopic method, the microfilarial rate of B. malayi in an endemic area of Narathiwat province was 1.38 per cent. The microfilarial densities ranged from 17 microfilariae/ml to 1,250 microfilariae/ml median = 50. The highest prevalence was found in the age group > 45-60 (4.69%). The lowest microfilarial rate was in the age group < or = 15 (0.37%). The infection in males was about three fold the number in females. A PCR-based method was employed to detect a B. malayi-specific Hha I repetitive DNA sequence with high specificity and sensitivity. The PCR assay will be useful in assisting the elimination program of lymphatic filariasis in control and monitoring the disease in Thailand.en_US
dc.description.affiliationDepartment of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationTriteeraprapab S, Karnjanopas K, Porksakorn C, Sai-Ngam A, Yentakam S, Loymak S. Lymphatic filariasis caused by Brugia malayi in an endemic area of Narathiwat Province, southern of Thailand. Journal of the Medical Association of Thailand. 2001 Jun; 84 Suppl 1(): S182-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43542
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshBrugia malayi --isolation & purificationen_US
dc.subject.meshChilden_US
dc.subject.meshEndemic Diseasesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFilariasis --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshLymphatic Diseases --diagnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPolymerase Chain Reaction --methodsen_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshRural Populationen_US
dc.subject.meshSampling Studiesen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleLymphatic filariasis caused by Brugia malayi in an endemic area of Narathiwat Province, southern of Thailand.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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