Pattern and outcome of neuroblastoma. A 10 year study.

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dc.contributor.authorKusumakumary, Pen_US
dc.contributor.authorAjithkumar, T Ven_US
dc.contributor.authorRatheesan, Ken_US
dc.contributor.authorChellam, V Gen_US
dc.contributor.authorNair, M Ken_US
dc.date.accessioned1998-03-26en_US
dc.date.accessioned2009-05-27T05:14:48Z
dc.date.available1998-03-26en_US
dc.date.available2009-05-27T05:14:48Z
dc.date.issued1998-03-26en_US
dc.description.abstractOBJECTIVE: To determine the clinical pattern and outcome of children with neuroblastoma. DESIGN: Retrospective analysis. SETTING: Hospital based information from the case sheets. SUBJECTS: 91 children with age upto 14 years treated in the Regional Cancer Center, Trivandrum. METHODS: Clinical presentation, metastatic pattern and treatment outcome were analyzed. RESULTS: Median age of the study group was 2.5 years with a male:female ratio of 1.6:1. Fifteen per cent children had early stage disease and 85% advanced disease. Five children with stage III and 22 with stage IV disease did not receive may active treatment. The remaining 64 children were evaluated for this analysis with a survival rate of 25%. Two of the four (50%) stage I, four of the six (83.3%) stage II, five of the 18 (27.7%) stage III, three of the 32 (9%) stage IV and two of the four (50%) stage IVs patients are long term survivors. CONCLUSIONS: Majority of the children (> 80%) presented with advanced disease and outcome remained poor. Only 27% of stage III and 9% of stage IV patients are long term survivors in our series. In future, approaches to detect disease at an early stage and aggressive therapeutic strategies in selected patients may improve survival.en_US
dc.description.affiliationDivision of Pediatric Oncology and Radiation Oncology, Regional Cencer Center, Trivandrum, Kerala.en_US
dc.identifier.citationKusumakumary P, Ajithkumar TV, Ratheesan K, Chellam VG, Nair MK. Pattern and outcome of neuroblastoma. A 10 year study. Indian Pediatrics. 1998 Mar; 35(3): 223-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/9428
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAdolescenten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshNeuroblastoma --diagnosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshSurvival Rateen_US
dc.titlePattern and outcome of neuroblastoma. A 10 year study.en_US
dc.typeJournal Articleen_US
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