Computed tomography‑guided percutaneous microwave ablation of patients 75 years of age and older with early‑stage nonsmall cell lung cancer.

dc.contributor.authorHan, X
dc.contributor.authorYang, X
dc.contributor.authorYe, X
dc.contributor.authorLiu, Q
dc.contributor.authorHuang, G
dc.contributor.authorWang, J
dc.contributor.authorLi, W
dc.contributor.authorZheng, A
dc.contributor.authorNi, Y
dc.contributor.authorMen, M
dc.date.accessioned2015-12-30T06:57:26Z
dc.date.available2015-12-30T06:57:26Z
dc.date.issued2015-12
dc.description.abstractBACKGROUND: We aimed to assess the clinical outcome of computed tomography (CT)‑guided percutaneous microwave ablation (MWA) in patients 75 years of age and older with early stage peripheral nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS: Twenty‑eight patients, aged ≥75 years, with Stage I and lymph node‑negative IIa peripheral NSCLC underwent CT‑guided percutaneous MWA in our hospital between July 2007 and March 2015. The overall 1‑, 2‑, 3‑, and 4‑year survival rates were estimated using Kaplan–Meier analysis. Adverse events were recorded. RESULTS: The median follow‑up time was 22.5 months. The overall median survival time (MST) was 35 months (95% confidence interval [CI] 22.3–47.7 months), and the cancer‑specific MST was 41.9 months (95% CI 38.8–49.9 months). The 1‑, 2‑, 3‑, and 4‑year overall survival rates were 91.7%, 76.5%, 47.9%, and 47.9%, while the cancer‑specific survival rates were 94.7%, 73.9%, 64.7%, and 64.7%, respectively. Median time to local progression was 28.0 months (95% CI 17.7–38.3 months). Major complications were included pneumothorax (21.4%, requiring drainage), pleural effusions (3.6%, requiring drainage), and pulmonary infection (3.6%). CONCLUSIONS: CT‑guided percutaneous MWA is safe and effective for the treatment of patients 75 years of age and older with medically inoperable early stage peripheral NSCLC.en_US
dc.identifier.citationHan X, Yang X, Ye X, Liu Q, Huang G, Wang J, Li W, Zheng A, Ni Y, Men M. Computed tomography‑guided percutaneous microwave ablation of patients 75 years of age and older with early‑stage nonsmall cell lung cancer. Indian Journal of Cancer. 2015 Dec; 52(6)Suppl_2: s56-s60.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/169240
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2015;volume=52;issue=6;spage=56;epage=60;aulast=Hanen_US
dc.subjectElderlyen_US
dc.subjectmicrowave ablationen_US
dc.subjectnonsmall cell lung canceren_US
dc.titleComputed tomography‑guided percutaneous microwave ablation of patients 75 years of age and older with early‑stage nonsmall cell lung cancer.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
ijc2015v52n6ps56.pdf
Size:
668.37 KB
Format:
Adobe Portable Document Format
Description:
Original article
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: